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| Content Provider | Royal Society of Chemistry (RSC) |
|---|---|
| Author | Zhu, Yongjun Liu, Sa Li, Lifeng Ren, Li Gao, Huichang Wang, Lin Chu, Minglei |
| Copyright Year | 2017 |
| Abstract | A novel bacterial cellulose/collagen–hydroxypropyltrimethyl ammonium chloride chitosan composite (BCC–H), as an ideal artificial hernia mesh, was synthesized by combining solution impregnation with the EDC/NHS chemical crosslinking method. Scanning electron microscopy was used to examine the morphology of the bacterial cellulose/collagen (BCC) and BCC–H composites. Infrared spectroscopy demonstrated that collagen and hydroxypropyltrimethyl ammonium chloride chitosan (HACC) were incorporated into the bacterial cellulose network successfully. Mechanical testing of the materials showed that the addition of HACC made the tensile strength decrease while the elongation at break was increased. Antibacterial assessment of the BCC–H composites revealed distinct growth inhibition against Escherichia coli and Staphylococcus aureus. In vitro cell experiments confirmed that the BCC–H composites had low cytotoxicity and good biocompatibility. |
| Starting Page | 11601 |
| Ending Page | 11607 |
| Page Count | 7 |
| File Format | HTM / HTML PDF |
| ISSN | 20462069 |
| Volume Number | 7 |
| Issue Number | 19 |
| Journal | RSC Advances |
| DOI | 10.1039/c6ra26216c |
| Language | English |
| Publisher | Royal Society of Chemistry |
| Access Restriction | Open |
| Subject Keyword | Infrared spectroscopy BCC Escherichia coli Cellulose Ultimate tensile strength Cytotoxicity N-Hydroxysuccinimide Scanning electron microscope Ammonium chloride Hernia Aureus Collagen HACC Biocompatibility Chitosan |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry Chemical Engineering |
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