NDLI: Synthesis of amphiphilic block-type macromolecular brushes with cleavable pendant chains and fabrication of micelle-templated polymer nanocapsules

Please wait, while we are loading the content...

One for all: cobalt-containing polymethacrylates for magnetic ceramics, block copolymerization, unexpected electrochemistry, and stimuli-responsiveness

Smart block copolymers of PVP and an alkylated PVP derivative: synthesis, characterization, thermoresponsive behaviour and self-assembly

Efficient red emission from poly(vinyl butyral) films doped with a novel europium complex based on a terpyridyl ancillary ligand: synthesis, structural elucidation by Sparkle/RM1 calculation, and photophysical properties

Organic–inorganic polyimides with double decker silsesquioxane in the main chains

Synthesis and in-depth characterization of reactive, uniform, crosslinked microparticles based on free radical copolymerization of 4-vinylbenzyl azide

An ultra-narrow bandgap derived from thienoisoindigo polymers: structural influence on reducing the bandgap and self-organization

Ultrathin free-standing polymer membranes with chemically responsive luminescence via consecutive photopolymerizations

Synthesis of amphiphilic block-type macromolecular brushes with cleavable pendant chains and fabrication of micelle-templated polymer nanocapsules

Back cover

Polymer Chemistry Vol -6

Polymer Chemistry Vol -5

Polymer Chemistry Vol -4

Polymer Chemistry Vol -3

Polymer Chemistry Vol -2

Polymer Chemistry Vol -1

Synthesis of amphiphilic block-type macromolecular brushes with cleavable pendant chains and fabrication of micelle-templated polymer nanocapsules

Content Provider	Royal Society of Chemistry (RSC)
Author	Han, Guangda Ju, Yuanyuan Zhao, Hanying
Copyright Year	2016
Abstract	Nanocapsules composed of cross-linked membranes and empty voids have found wide applications as drug delivery carriers, sensors and nanosized reactors. In this research, a new method for the fabrication of functional nanocapsules is proposed. Poly(oligo(ethylene glycol) monomethyl ether methacrylate)-block-(poly(tert-butyl methacrylate)-graft-poly(2-(dimethylamino)ethyl methacrylate)) (POEGMA-b-(PtBMA-g-PDMAEMA)) brush polymers were synthesized by two-step reversible addition–fragmentation chain transfer polymerization and atom transfer radical polymerization. The pendant PDMAEMA chains were grafted to the backbones through disulfide bonds. In acidic water, the brush polymer chains self-assembled into micelles with PtBMA cores and POEGMA/PDMAEMA mixed coronae. Upon cross-linking of PDMAEMA chains and cleavage of the disulfides with tri-n-butylphosphine, hydrophilic nanocapsules were obtained. The brush polymers were analyzed by gel permeation chromatography and 1H NMR. The sizes and the morphologies of the micelles and the nanocapsules were characterized by transmission electron microscopy, atomic force microscopy and dynamic light scattering. The thiol groups on the inner walls of the nanocapsules undergo a thiol–ene reaction with fluorescein O-methacrylate (FMA). The photoluminescence results demonstrate that FMA molecules are able to pass through the membranes and functionalization of the nanocapsules can be performed.
Starting Page	1197
Ending Page	1206
Page Count	10
File Format	HTM / HTML PDF
ISSN	17599954
Volume Number	7
Issue Number	5
Journal	Polymer Chemistry
DOI	10.1039/c5py01940k
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Atom-transfer radical-polymerization Ethylene glycol Thiol Ether PDMAEMA Butyl group Photoluminescence Polymer brush Polymerization Drug delivery Oligomer Gel permeation chromatography Chain transfer Transmission electron microscopy Atomic-force microscopy Dynamic light scattering Disulfide Fluorescein FMA Hydrophile Nuclear magnetic resonance
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Biochemistry Bioengineering Biomedical Engineering Polymers and Plastics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Synthesis of amphiphilic block-type macromolecular brushes with cleavable pendant chains and fabrication of micelle-templated polymer nanocapsules

Facile synthesis of thiol-functionalized amphiphilic polylactide–methacrylic diblock copolymers

Thiol and pH dual-responsive dynamic covalent shell cross-linked micelles for triggered release of chemotherapeutic drugs

UV-cleavable unimolecular micelles: synthesis and characterization toward photocontrolled drug release carriers

Construction of PEG-based amphiphilic brush polymers bearing hydrophobic poly(lactic acid) side chains via successive RAFT polymerization and ROP

Role of branching of hydrophilic domain on physicochemical properties of amphiphilic macromolecules

Exploring the potential of linear polymer structures for the synthesis of fluorescent gold nanoclusters

Synthesis and modification of thermoresponsive poly(oligo(ethylene glycol) methacrylate) via catalytic chain transfer polymerization and thiol–ene Michael addition

Synthesis, Characterization, Conformation in Solution, and Thermoresponsiveness of Polymer Brushes of methoxy[oligo (propylene glycol)-block-oligo(ethylene glycol)]methacrylate and N-[3-(dimethylamino)propyl]methacrylamide Obtained via RAFT Polymerization.

Synthesis of amphiphilic block-type macromolecular brushes with cleavable pendant chains and fabrication of micelle-templated polymer nanocapsules

Similar Documents

Synthesis of amphiphilic block-type macromolecular brushes with cleavable pendant chains and fabrication of micelle-templated polymer nanocapsules

Facile synthesis of thiol-functionalized amphiphilic polylactide–methacrylic diblock copolymers

Thiol and pH dual-responsive dynamic covalent shell cross-linked micelles for triggered release of chemotherapeutic drugs

UV-cleavable unimolecular micelles: synthesis and characterization toward photocontrolled drug release carriers

Construction of PEG-based amphiphilic brush polymers bearing hydrophobic poly(lactic acid) side chains via successive RAFT polymerization and ROP

Role of branching of hydrophilic domain on physicochemical properties of amphiphilic macromolecules

Exploring the potential of linear polymer structures for the synthesis of fluorescent gold nanoclusters

Synthesis and modification of thermoresponsive poly(oligo(ethylene glycol) methacrylate) via catalytic chain transfer polymerization and thiol–ene Michael addition

Synthesis, Characterization, Conformation in Solution, and Thermoresponsiveness of Polymer Brushes of methoxy[oligo (propylene glycol)-block-oligo(ethylene glycol)]methacrylate and N-[3-(dimethylamino)propyl]methacrylamide Obtained via RAFT Polymerization.

Synthesis of amphiphilic block-type macromolecular brushes with cleavable pendant chains and fabrication of micelle-templated polymer nanocapsules