NDLI: Silver nanoparticle-embedded polymersome nanocarriers for the treatment of antibiotic-resistant infections

Please wait, while we are loading the content...

Nano electrochemical reactors of Fe₂O₃ nanoparticles embedded in shells of nitrogen-doped hollow carbon spheres as high-performance anodes for lithium-ion batteries

Nanocellulose coupled flexible polypyrrole@graphene oxide composite paper electrodes with high volumetric capacitance

Conductivity scaling in supercritical percolation of nanoparticles – not a power law

A tunable submicro-optofluidic polymer filter based on guided-mode resonance

Compact discs as versatile cost-effective substrates for releasable nanopatterned aluminium films

High yield fabrication of hollow vesica-like silicon based on the Kirkendall effect and its application to energy storage

Multilayered core–satellite nanoassemblies with fine-tunable broadband plasmon resonances

Giant reversible nanoscale piezoresistance at room temperature in Sr₂IrO₄ thin films

Morphological evolution of 2D Rh nanoplates to 3D Rh concave nanotents, hierarchically stacked nanoframes, and hierarchical dendrites

Incorporation of organic crystals into the interspace of oriented nanocrystals: morphologies and properties

Concave gold nanocube assemblies as nanotraps for surface-enhanced Raman scattering-based detection of proteins

In situ powder X-ray diffraction study of magnetic CoFe₂O₄ nanocrystallite synthesis

Soft landing of bare nanoparticles with controlled size, composition, and morphology

Scribable multi-walled carbon nanotube-silicon nanocomposites: a viable lithium-ion battery system

Silver nanoparticle-embedded polymersome nanocarriers for the treatment of antibiotic-resistant infections

Multiwalled carbon nanotube@a-C@Co₉S₈ nanocomposites: a high-capacity and long-life anode material for advanced lithium ion batteries

Novel energy relay dyes for high efficiency dye-sensitized solar cells

Spherical core–shell magnetic particles constructed by main-chain palladium N-heterocyclic carbenes

Microsphere assembly of TiO₂ mesoporous nanosheets with highly exposed (101) facets and application in a light-trapping quasi-solid-state dye-sensitized solar cell

An effective non-covalent grafting approach to functionalize individually dispersed reduced graphene oxide sheets with high grafting density, solubility and electrical conductivity

Highly air stable passivation of graphene based field effect devices

Surface passivation of a photonic crystal band-edge laser by atomic layer deposition of SiO₂ and its application for biosensing

Tunable doping of graphene nanoribbon arrays by chemical functionalization

Controlled partial-exfoliation of graphite foil and integration with MnO₂ nanosheets for electrochemical capacitors

The aspect ratio effect of drug nanocrystals on cellular internalization efficiency, uptake mechanisms, and in vitro and in vivo anticancer efficiencies

Morphogenesis mechanisms in the solvothermal synthesis of BaTiO₃ from titanate nanorods and nanotubes

Mo-doped SnO₂ mesoporous hollow structured spheres as anode materials for high-performance lithium ion batteries

Enzyme responsive mesoporous silica nanoparticles for targeted tumor therapy in vitro and in vivo

A novel electrochemiluminescent immunosensor based on CdS-coated ZnO nanorod arrays for HepG2 cell detection

Near-field asymmetries in plasmonic resonators

Dirac point movement and topological phase transition in patterned graphene

In situ imaging and control of layer-by-layer femtosecond laser thinning of graphene

Gigantic enhancement in the dielectric properties of polymer-based composites using core/shell MWCNT/amorphous carbon nanohybrids

Platinum-decorated reduced graphene oxide/polyaniline:poly(4-styrenesulfonate) hybrid paste for flexible dipole tag-antenna applications

A high-performance supercapacitor of vertically-oriented few-layered graphene with high-density defects

Morphology-controlled In₂O₃ nanostructures enhance the performance of photoelectrochemical water oxidation

Growth and spectroscopic characterization of monolayer and few-layer hexagonal boron nitride on metal substrates

3D plasmonic nanoantennas integrated with MEA biosensors

Reduced graphene oxide hydrogel film with a continuous ion transport network for supercapacitors

Megranate-like nanoreactor with multiple cores and an acidic mesoporous shell for a cascade reaction

Integration of a nanostructured dielectrophoretic device and a surface-enhanced Raman probe for highly sensitive rapid bacteria detection

Surface dangling bonds are a cause of B-type blinking in Si nanoparticles

A hot-spot-active magnetic graphene oxide substrate for microRNA detection based on cascaded chemiluminescence resonance energy transfer

Nano-thermometers with thermo-sensitive polymer grafted USPIOs behaving as positive contrast agents in low-field MRI

An ultra-sensitive impedimetric immunosensor for detection of the serum oncomarker CA-125 in ovarian cancer patients

Fog-like fluffy structured N-doped carbon with a superior oxygen reduction reaction performance to a commercial Pt/C catalyst

Inside back cover

Back cover

Nanoscale Vol - 7 Issue - 7

Nanoscale Vol - 7 Issue - 6

Nanoscale Vol - 7 Issue - 5

Silver nanoparticle-embedded polymersome nanocarriers for the treatment of antibiotic-resistant infections

Content Provider	Royal Society of Chemistry (RSC)
Author	Ven, Anne L. de Singleton, Gloria L. Geilich, Benjamin M. Sridhar, Srinivas Sepúlveda, Liuda J. Webster, Thomas J.
Copyright Year	2015
Abstract	The rapidly diminishing number of effective antibiotics that can be used to treat infectious diseases and associated complications in a physician's arsenal is having a drastic impact on human health today. This study explored the development and optimization of a polymersome nanocarrier formed from a biodegradable diblock copolymer to overcome bacterial antibiotic resistance. Here, polymersomes were synthesized containing silver nanoparticles embedded in the hydrophobic compartment, and ampicillin in the hydrophilic compartment. Results showed for the first time that these silver nanoparticle-embedded polymersomes (AgPs) inhibited the growth of Escherichia coli transformed with a gene for ampicillin resistance (bla) in a dose-dependent fashion. Free ampicillin, AgPs without ampicillin, and ampicillin polymersomes without silver nanoparticles had no effect on bacterial growth. The relationship between the silver nanoparticles and ampicillin was determined to be synergistic and produced complete growth inhibition at a silver-to-ampicillin ratio of 1 : 0.64. In this manner, this study introduces a novel nanomaterial that can effectively treat problematic, antibiotic-resistant infections in an improved capacity which should be further examined for a wide range of medical applications.
Starting Page	3511
Ending Page	3519
Page Count	9
File Format	HTM / HTML PDF
ISSN	20403364
Volume Number	7
Issue Number	8
Journal	Nanoscale
DOI	10.1039/c4nr05823b
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Biodegradation Gene Ampicillin Escherichia coli Polymersome Copolymer Antimicrobial resistance Hydrophobe Hydrophile Mathematical optimization
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Silver nanoparticle-embedded polymersome nanocarriers for the treatment of antibiotic-resistant infections

Effect of ultraviolet irradiation and chlorination on ampicillin-resistant Escherichia coli and its ampicillin resistance gene

Colonization dynamics of ampicillin-resistant escherichia coli in the infantile colonic microbiota.

Overexpression of AmpC Promotes Bacteriophage Lysis of Ampicillin-Resistant Escherichia coli

Diverse Gene Cassette Arrays Prevail in Commensal Escherichia coli From Intensive Farming Swine in Four Provinces of China

Amphiphilic oligomer-based micelles as cisplatin nanocarriers for cancer therapy

Biological coating of paper using silver nanoparticles

Isolation of extraintestinal pathogenic escherichia coli from diarrheic dogs and their antimicrobial resistance profile.

Ampicillin usage and ampicillin resistant (ampr) plasmids mediated escherichia coli isolated from diarrheagenic patients attending some teaching hospital in nigeria.

Silver nanoparticle-embedded polymersome nanocarriers for the treatment of antibiotic-resistant infections

Similar Documents

Silver nanoparticle-embedded polymersome nanocarriers for the treatment of antibiotic-resistant infections

Effect of ultraviolet irradiation and chlorination on ampicillin-resistant Escherichia coli and its ampicillin resistance gene

Colonization dynamics of ampicillin-resistant escherichia coli in the infantile colonic microbiota.

Overexpression of AmpC Promotes Bacteriophage Lysis of Ampicillin-Resistant Escherichia coli

Diverse Gene Cassette Arrays Prevail in Commensal Escherichia coli From Intensive Farming Swine in Four Provinces of China

Amphiphilic oligomer-based micelles as cisplatin nanocarriers for cancer therapy

Biological coating of paper using silver nanoparticles

Isolation of extraintestinal pathogenic escherichia coli from diarrheic dogs and their antimicrobial resistance profile.

Ampicillin usage and ampicillin resistant (ampr) plasmids mediated escherichia coli isolated from diarrheagenic patients attending some teaching hospital in nigeria.

Silver nanoparticle-embedded polymersome nanocarriers for the treatment of antibiotic-resistant infections