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| Content Provider | Royal Society of Chemistry (RSC) |
|---|---|
| Author | Flahaut, Emmanuel Zanni, Elena Bellis, Giovanni De Rapino, Stefania Uccelletti, Daniela Monthioux, Marc Palleschi, Claudio Fiorito, Silvana Olivi, Massimiliano Talora, Claudio Sarto, Maria Sabrina |
| Copyright Year | 2013 |
| Abstract | In the last years carbon nanotubes have attracted increasing attention for their potential applications in the biomedical field as diagnostic and therapeutic nano tools. Here we investigate the antimicrobial activity of different fully characterized carbon nanotube types (single walled, double walled and multi walled) on representative pathogen species: Gram-positive Staphylococcus aureus, Gram-negative Pseudomonas aeruginosa and the opportunistic fungus Candida albicans. Our results show that all the carbon nanotube types possess a highly significant antimicrobial capacity, even though they have a colony forming unit capacity and induction of oxidative stress in all the microbial species to a different extent. Moreover, scanning electron microscopy analysis revealed that the microbial cells were wrapped or entrapped by carbon nanotube networks. Our data taken together suggest that the reduced capacity of microbial cells to forming colonies and their oxidative response could be related to the cellular stress induced by the interactions of pathogens with the CNT network. |
| Starting Page | 9023 |
| Ending Page | 9029 |
| Page Count | 7 |
| File Format | HTM / HTML PDF |
| ISSN | 20403364 |
| Volume Number | 5 |
| Issue Number | 19 |
| Journal | Nanoscale |
| DOI | 10.1039/c3nr02091f |
| Language | English |
| Publisher | Royal Society of Chemistry |
| Access Restriction | Open |
| Subject Keyword | Carbon nanotube Antimicrobial Candida albicans Oxidative stress Aureus CNT Gram-positive bacteria Pseudomonas aeruginosa Gram-negative bacteria Pathogen Colony-forming unit Scanning electron microscope |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology |
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