NDLI: On-chip syringe pumps for picoliter-scale liquid manipulation

Content Provider	Royal Society of Chemistry (RSC)
Author	Saika, Tomohiko Fujita, Hiroyuki Konishi, Satoshi Yokokawa, Ryuji Nakayama, Testuya
Copyright Year	2006
Abstract	On-chip microsyringes are developed by integrating parallel micro actuators and a microfluidic chip. Sliders of an Electrostatically Controlled Linear Inchworm Actuator (ECLIA) are applied to manipulate microsyringes in the nanometer range, which allows liquid control on the picoliter scale. ECLIA drives sliders in parallel with high accuracy and a large stroke. The requirements for syringe performance, such as parallel and precise liquid control, can be satisfied by the above features of ECLIA. A total volume of a few µL is manipulated at a flow rate of 19–27 pL s−1 by the stepwise motion of ECLIA sliders in a fluidic channel. Microsyringes integrated into the driving mechanism are a key component of Micro Total Analysis Systems (μTAS) due to the possibility of on-chip integration. In addition, the proposed approach has a significant implication in MEMS in that the electrostatic micro actuator performs a physical task that affects the outside structure.
Starting Page	1062
Ending Page	1066
Page Count	5
File Format	HTM / HTML PDF
ISSN	14730197
Volume Number	6
Issue Number	8
Journal	Lab on a Chip
DOI	10.1039/b603938c
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Subscribed
Subject Keyword	Microelectromechanical systems Total analysis system Micro Total Analysis Systems Sliders Geometer moth Nanometre Litre ECLIA Actuator
Content Type	Text
Resource Type	Article
Subject	Chemistry Nanoscience and Nanotechnology Biochemistry Bioengineering Biomedical Engineering

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