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| Content Provider | Royal Society of Chemistry (RSC) |
|---|---|
| Author | Fuerstman, Michael J. Sia, Samuel K. Garstecki, Piotr Fischbach, Michael A. Whitesides, George M. |
| Copyright Year | 2006 |
| Abstract | This paper demonstrates a methodology for micromixing that is sufficiently simple that it can be used in portable microfluidic devices. It illustrates the use of the micromixer by incorporating it into an elementary, portable microfluidic system that includes sample introduction, sample filtration, and valving. This system has the following characteristics: (i) it is powered with a single hand-operated source of vacuum, (ii) it allows samples to be loaded easily by depositing them into prefabricated wells, (iii) the samples are filtered in situ to prevent clogging of the microchannels, (iv) the structure of the channels ensure mixing of the laminar streams by interaction with bubbles of gas introduced into the channels, (v) the device is prepared in a single-step soft-lithographic process, and (vi) the device can be prepared to be resistant to the adsorption of proteins, and can be used with or without surface-active agents. |
| Starting Page | 207 |
| Ending Page | 212 |
| Page Count | 6 |
| File Format | HTM / HTML PDF |
| ISSN | 14730197 |
| Volume Number | 6 |
| Issue Number | 2 |
| Journal | Lab on a Chip |
| DOI | 10.1039/b510843h |
| Language | English |
| Publisher | Royal Society of Chemistry |
| Access Restriction | Subscribed |
| Subject Keyword | Microchannel (microtechnology) Laminar flow Adsorption Micromixer |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry Nanoscience and Nanotechnology Biochemistry Bioengineering Biomedical Engineering |
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