NDLI: Antigen detection using polymerization-based amplification

Content Provider	Royal Society of Chemistry (RSC)
Author	Bowman, Christopher N. Sikes, Hadley D. Jenison, Robert
Copyright Year	2009
Abstract	The influenza virus has been subtyped from crude lysates using polymerization-based amplification. In this novel chemical approach to detection, signal amplification was achieved by coupling a polymerization reaction to a protein–protein recognition event. This particular method shows promise due to its advantages over the techniques currently employed in commercial assays in terms of cost, robustness, and unambiguity of test results. Instrumentation is not required to see the crosslinked hydrogel “readout”, and no false positives or false negatives were observed above the limit of detection.
Starting Page	653
Ending Page	656
Page Count	4
File Format	HTM / HTML PDF
ISSN	14730197
Volume Number	9
Issue Number	5
Journal	Lab on a Chip
DOI	10.1039/b816198d
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Virus Influenza Polymerization Gel
Content Type	Text
Resource Type	Article
Subject	Chemistry Nanoscience and Nanotechnology Biochemistry Bioengineering Biomedical Engineering

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Antigen detection using polymerization-based amplification