NDLI: Functionalized magnetic microparticle-based colorimetric platform for influenza A virus detection

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Functionalized magnetic microparticle-based colorimetric platform for influenza A virus detection

Content Provider	Scilit
Author	Chen, Chaohui Zou, Zhong Chen, Lu Ji, Xinghu He, Zhike
Copyright Year	2016
Description	Journal: Nanotechnology A colorimetric platform for influenza A virus detection was developed by using the high efficiency of enzymatic catalysis and the reduction of gold ions with hydrogen peroxide. Aptamer-functionalized magnetic microparticles were synthesized to capture the influenza A virus. This was followed by the binding of ConA-GOx-AuNPs to the H3N2 virus through the ConA-glycan interaction. The sandwich complex was subsequently dispersed in glucose solution to trigger an enzymatic reaction to produce hydrogen peroxide, which controlled the growth of gold nanoparticles and produced colored solutions. The determination of H3N2 concentration was realized by comparing the two differently colored gold nanoparticles. This method could detect the target virus as low as 11.16 μg ml−1. Furthermore, it opens new opportunities for sensitive and colorimetric detection of viruses and proteins.
Related Links	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103194/pdf
Ending Page	435102
Page Count	1
Starting Page	435102
ISSN	09574484
e-ISSN	13616528
DOI	10.1088/0957-4484/27/43/435102
Journal	Nanotechnology
Issue Number	43
Volume Number	27
Language	English
Publisher	IOP Publishing
Publisher Date	2016-09-22
Access Restriction	Open
Subject Keyword	Journal: Nanotechnology Analytical Chemistry Influenza A Virus Magnetic Microparticles
Content Type	Text
Resource Type	Article
Subject	Chemistry Nanoscience and Nanotechnology Mechanics of Materials Mechanical Engineering Bioengineering Electrical and Electronic Engineering

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