NDLI: Red wine extract decreases pro-inflammatory markers, nuclear factor-κB and inducible NOS, in experimental metabolic syndrome

Please wait, while we are loading the content...

The effects of daily supplementation of Dendrobium huoshanense polysaccharide on ethanol-induced subacute liver injury in mice by proteomic analysis

Glycation is regulated by isoflavones

The effect of chicken extract on ERK/CREB signaling is ApoE isoform-dependent

New insights into the effects of formulation type and compositional mixtures on the antioxidant and cytotoxic activities of dietary supplements based-on hepatoprotective plants

Immunomodulating effects of casein-derived peptides QEPVL and QEPV on lymphocytes in vitro and in vivo

Protective effects of oat oil on deltamethrin-induced reprotoxicity in male mice

Comparative studies of oral administration of marine collagen peptides from Chum Salmon (Oncorhynchus keta) pre- and post-acute ethanol intoxication in female Sprague-Dawley rats

Nutraceutical potential of Aerva lanata (L.) Juss. ex Schult ameliorates secondary complications in streptozotocin-induced diabetic rats

The effect of red wine consumption on hormonal reproductive parameters and total antioxidant status in young adult male rats

Inhibition of allergic airway inflammation through the blockage of NF-κB activation by ellagic acid in an ovalbumin-induced mouse asthma model

Effect and mechanism of mackerel (Pneumatophorus japonicus) peptides for anti-fatigue

Modulation of hyperglycemia and TNFα-mediated inflammation by helichrysum and grapefruit extracts in diabetic db/db mice

Phytochemical characterization and antioxidant activity of the cladodes of Opuntia macrorhiza (Engelm.) and Opuntia microdasys (Lehm.)

Piceid presents antiproliferative effects in intestinal epithelial Caco-2 cells, effects unrelated to resveratrol release

The effect of anthocyans on the expression of selected phase II xenobiotic-metabolizing enzymes in primary cultures of human hepatocytes

Cytotoxicity comparison of quercetin and its metabolites from in vitro fermentation of several gut bacteria

The effect of heat treatment of thylakoids on their ability to inhibit in vitro lipase/co-lipase activity

Fruits, vegetables and their polyphenols protect dietary lipids from oxidation during gastric digestion

Vitamin C exerts beneficial hepatoprotection against Concanavalin A-induced immunological hepatic injury in mice through inhibition of NF-κB signal pathway

Antitumor efficacy in H22 tumor bearing mice and immunoregulatory activity on RAW 264.7 macrophages of polysaccharides from Talinum triangulare

Differential effects of lipid fractions from silver carp brain on human cervical carcinoma cells in vitro

Red wine extract decreases pro-inflammatory markers, nuclear factor-κB and inducible NOS, in experimental metabolic syndrome

Effects of the polyphenol content on the anti-diabetic activity of Cinnamomum zeylanicum extracts

Tocotrienol modulates crucial lipid metabolism-related genes in differentiated 3T3-L1 preadipocytes

Asn-Trp dipeptides improve the oxidative stress and learning dysfunctions in d-galactose-induced BALB/c mice

A low calorie morning meal prevents the decline of hepatic glycogen stores: a pilot in vivo¹³C magnetic resonance study

Neuroprotective effects of dietary supplement Kang-fu-ling against high-power microwave through antioxidant action

Protective effects of piperine against copper-ascorbate induced toxic injury to goat cardiac mitochondria in vitro

In vitro antioxidant activities and anti-proliferative properties of the functional herb Abrus cantoniensis and its main alkaloid abrine

Antrodia camphorata induces G₁ cell-cycle arrest in human premyelocytic leukemia (HL-60) cells and suppresses tumor growth in athymic nude mice

Extremely low frequency electromagnetic field exposure causes cognitive impairment associated with alteration of the glutamate level, MAPK pathway activation and decreased CREB phosphorylation in mice hippocampus: reversal by procyanidins extracted from the lotus seedpod

Phenolic metabolites and substantial microbiome changes in pig feces by ingesting grape seed proanthocyanidins

Dietary sweet potato (Ipomoea batatas L.) leaf extract attenuates hyperglycaemia by enhancing the secretion of glucagon-like peptide-1 (GLP-1)

The nutritional composition and anti-hypertensive activity on spontaneously hypertensive rats of sipuncula Phascolosoma esculenta

Superior prebiotic and physicochemical properties of novel dextran from Weissella cibaria JAG8 for potential food applications

Effect of broccoli phytochemical extract on release of fatty acids from salmon muscle and salmon oil during in vitro digestion

Microbial diversity and flavor formation in onion fermentation

Resveratrol prevents cigarette smoke-induced keratinocytes damage

A grape seed extract increases active glucagon-like peptide-1 levels after an oral glucose load in rats

Effects of vitamin D supplements on influenza A illness during the 2009 H1N1 pandemic: a randomized controlled trial

Esculetin inhibits the inflammatory response by inducing heme oxygenase-1 in cocultured macrophages and adipocytes

Back cover

Food & Function Vol - 5 Issue - 8

Food & Function Vol - 5 Issue - 7

Food & Function Vol - 5 Issue - 6

Food & Function Vol - 5 Issue - 5

Food & Function Vol - 5 Issue - 4

Food & Function Vol - 5 Issue - 3

Food & Function Vol - 5 Issue - 2

Food & Function Vol -4

Food & Function Vol -3

Food & Function Vol -2

Food & Function Vol -1

Red wine extract decreases pro-inflammatory markers, nuclear factor-κB and inducible NOS, in experimental metabolic syndrome

Content Provider	Royal Society of Chemistry (RSC)
Author	Vranková, Stanislava Barta, Andrej Cebová, Martina Čierna, Zuzana Kovácsová, Mária Pechánová, Olga Janega, Pavol Klimentová, Jana Jakovljevic, Vladimir Matúsková, Zuzana
Copyright Year	2014
Abstract	We aimed to analyse the effects of alcohol-free Alibernet red wine extract (AWE) on nitric oxide synthase (NOS) activity and pro-inflammatory markers such as nuclear factor-κB (NFκB) and inducible NOS (iNOS) protein expression in experimental metabolic syndrome. Young 6 week-old male Wistar Kyoto (WKY) and obese, spontaneously hypertensive rats (SHR/N-cp) were divided into control groups and groups treated with AWE (24.2 mg per kg per day) for 3 weeks (n = 6 in each group). Total NOS activity and endothelial NOS (eNOS), iNOS and NFκB (p65) protein expressions were determined in the heart left ventricle and aorta by Western blot and immunohistochemical analysis. All parameters investigated significantly increased in the aorta of SHR/N-cp rats. Pro-inflammatory markers such as NFκB and iNOS were increased in the left ventricle as well. AWE treatment did not affect total NOS activity and eNOS expression in the aorta; however, it was able to decrease NFκB and iNOS protein expression in both the left ventricle and aorta. In conclusion, in the cardiovascular system, Alibernet red wine extract decreased NFκB and iNOS protein expressions elevated as a consequence of developed metabolic syndrome. This effect may represent one of the protective, anti-inflammatory properties of Alibernet red wine polyphenols on cardiovascular risk factors related to metabolic syndrome.
Starting Page	2202
Ending Page	2207
Page Count	6
File Format	HTM / HTML PDF
ISSN	20426496
Volume Number	5
Issue Number	9
Journal	Food & Function
DOI	10.1039/c4fo00097h
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Wistar Kyoto Alibernet Nitric oxide synthase NF-κB Protein Syndrome WKY Endothelial NOS Ventricle (heart) Aorta Western blot
Content Type	Text
Resource Type	Article
Subject	Medicine Food Science

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Intestinal anti-inflammatory activity of red wine extract: unveiling the mechanisms in colonic epithelial cells

Oxide; NOS: Nitric Oxide Synthase; iNOS: Inducible Nitric Oxide Synthase; ecNOS: Endothelial Nitric Oxide Synthase and nNOS: Neuronal Nitric Oxide Synthase

Regulatory role of nitric oxide in civilisation diseases, slovak academy of sciences,.

Zinc regulates iNOS-derived nitric oxide formation in endothelial cells

The red‐vine‐leaf extract AS195 increases nitric oxide synthase–dependent nitric oxide generation and decreases oxidative stress in endothelial and red blood cells

Soybean glyceollins mitigate inducible nitric oxide synthase and cyclooxygenase-2 expression levels via suppression of the NF-κB signaling pathway in RAW 264.7 cells.

Crystal Structures of Zinc-free and -bound Heme Domain of Human Inducible Nitric-oxide Synthase IMPLICATIONS FOR DIMER STABILITY AND COMPARISON WITH ENDOTHELIAL NITRIC-OXIDE SYNTHASE

Red wine polyphenols enhance endothelial nitric oxide synthase expression and subsequent nitric oxide release from endothelial cells.

Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor

Red wine extract decreases pro-inflammatory markers, nuclear factor-κB and inducible NOS, in experimental metabolic syndrome

Similar Documents

Intestinal anti-inflammatory activity of red wine extract: unveiling the mechanisms in colonic epithelial cells

Oxide; NOS: Nitric Oxide Synthase; iNOS: Inducible Nitric Oxide Synthase; ecNOS: Endothelial Nitric Oxide Synthase and nNOS: Neuronal Nitric Oxide Synthase

Regulatory role of nitric oxide in civilisation diseases, slovak academy of sciences,.

Zinc regulates iNOS-derived nitric oxide formation in endothelial cells

The red‐vine‐leaf extract AS195 increases nitric oxide synthase–dependent nitric oxide generation and decreases oxidative stress in endothelial and red blood cells

Soybean glyceollins mitigate inducible nitric oxide synthase and cyclooxygenase-2 expression levels via suppression of the NF-κB signaling pathway in RAW 264.7 cells.

Crystal Structures of Zinc-free and -bound Heme Domain of Human Inducible Nitric-oxide Synthase IMPLICATIONS FOR DIMER STABILITY AND COMPARISON WITH ENDOTHELIAL NITRIC-OXIDE SYNTHASE

Red wine polyphenols enhance endothelial nitric oxide synthase expression and subsequent nitric oxide release from endothelial cells.

Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor

Red wine extract decreases pro-inflammatory markers, nuclear factor-κB and inducible NOS, in experimental metabolic syndrome