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Effective compounds in the fruit of Muntingia calabura Linn. cultivated in Taiwan evaluated with scavenging free radicals and suppressing LDL oxidation

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Food & Function Vol - 8 Issue - 3

Food & Function Vol - 8 Issue - 2

Food & Function Vol - 8 Issue - 1

Food & Function Vol -7

Food & Function Vol -6

Food & Function Vol -5

Food & Function Vol -4

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Food & Function Vol -2

Food & Function Vol -1

Effective compounds in the fruit of Muntingia calabura Linn. cultivated in Taiwan evaluated with scavenging free radicals and suppressing LDL oxidation

Content Provider	Royal Society of Chemistry (RSC)
Author	Chen, Yi-Chen Lin, Jau-Tien Chen, Ting-Yu Yang, Deng-Jye Chang, Yan-Zin
Copyright Year	2017
Abstract	Scavenging effect of 2,2-diphenyl -2-picrylhydrazyl hydrate (DPPH) radicals, inhibitory effect of low-density lipoprotein (LDL) oxidation, Trolox equivalent antioxidant capacity (TEAC), and phenolic contents were used for the activity-guided separation to identify the effective compounds of Muntingia calabura Linn. fruit. Its ethanol extract with higher phenolic content and antioxidant activities was subjected to silica gel column chromatographic separation, which was sequentially eluted with n-hexane, 10–90% ethyl acetate (EA) in n-hexane, EA, EA/acetone (50/50, v/v), acetone, acetone/methanol (MeOH) (50/50, v/v), and MeOH; fifteen fractions (Fr. 1–15) were obtained. Fractions 13 and 14 with better antioxidant effects were mixed followed by purification of the effective compounds using HPLC. Two major compounds were isolated and identified as gallic acid and 1,2-benzenedicarboxylic acid diisooctyl ester through high performance liquid chromatography-mass spectrometry (HPLC-MS) and nuclear magnetic resonance (NMR) measurements. Their amounts in the fruit were 3.76 and 4.62 mg g−1. This study is the first report to clarify the effective antioxidant compounds of M. calabura Linn. fruit.
Starting Page	1504
Ending Page	1511
Page Count	8
File Format	HTM / HTML PDF
ISSN	20426496
Volume Number	8
Issue Number	4
Journal	Food & Function
DOI	10.1039/c7fo00059f
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	TEAC EA Linn Hydrate DPPH Lipoprotein Low-density lipoprotein Trolox equivalent antioxidant capacity TEAC Corporation Muntingia Linn Records Ethanol Antioxidant Silica gel Chromatography Hexane Ethyl acetate Acetone Methanol High-performance liquid chromatography Acid Ester Liquid chromatography\u2013mass spectrometry Nuclear magnetic resonance
Content Type	Text
Resource Type	Article
Subject	Medicine Food Science

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Chromatographic fingerprinting and free-radical scavenging activity of ethanol extracts of Muntingia calabura L. leaves and stems

DPPH RADICAL SCAVENGING ACTIVITY OF AQUEOUS FRACTION FROM ETHANOLIC EXTRACT OF TALOK FRUIT (Muntingia calabura L.)

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In Vitro Antioxidant Activity of Extracts from Fruits of Muntingia calabura Linn. from India

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Abbreviations AS : Atherosclerosis LDL : Low density lipoprotein CVD : Cardiovascular disease UA : Uric acid BMI : Body mass index TC : Total cholesterol HDL : High density lipoprotein TG : Tryglicerides TEAC : Trolox equivalent antioxidant capacity

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Effective compounds in the fruit of Muntingia calabura Linn. cultivated in Taiwan evaluated with scavenging free radicals and suppressing LDL oxidation

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