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Analytical Methods Vol - 3 Issue - 5

Analytical Methods Vol - 3 Issue - 4

Analytical Methods Vol - 3 Issue - 3

Analytical Methods Vol - 3 Issue - 2

Analytical Methods Vol -2

Analytical Methods Vol -1

Bio-Raman spectroscopy: a potential clinical analytical method assisting in disease diagnosis

Content Provider	Royal Society of Chemistry (RSC)
Author	Chen, Pu Shen, Aiguo Hu, Jiming Zhou, Xiaodong
Copyright Year	2011
Abstract	With the technical progress in lasers, charge coupled device detectors, and fiber-optic probes, Raman spectroscopy (RS) is enjoying a strong resurgence in the field of biomedical science, especially in disease diagnosis. During this time we have witnessed more and more in vitro and in vivo applications of RS, and increasingly frequent reports of its utility. RS enables the extraction of biochemical signatures from biological tissues, and in conjunction with different statistic algorithms, the spectral data with various pathologic attributions can be differentiated and classified depending on their spectral differences, e.g., peak area, peak height or peak shape. This makes RS a potential clinical analytical technique for rapid and non-destructive diagnosis of human diseases. This paper is a review of the biomedical applications of Raman spectroscopic techniques in diagnostics. First, a brief illumination of RS instrumentation and algorithms for data analysis is introduced. Then wide utilization of RS in disease diagnosis is reviewed categorized by different tissues and organs, including brain, eye, body surface organs (breast, skin), abdominal organs (stomach, esophagus, colon, liver), thoracic organs (arteries, lung), reproductive and urinary organs (prostate, cervix, bladder) and hard tissue (bone, teeth). Some other work from our group are also introduced.
Starting Page	1257
Ending Page	1269
Page Count	13
File Format	HTM / HTML PDF
ISSN	17599660
Volume Number	3
Issue Number	6
Journal	Analytical Methods
DOI	10.1039/c1ay05039g
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Charge-coupled device Urinary system Large intestine Liver Lung Raman Bone Raman spectroscopy Cervix Prostate Esophagus
Content Type	Text
Resource Type	Article
Subject	Analytical Chemistry Engineering Chemical Engineering

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