NDLI: Analysis of alternatives for insulinizing patients to achieve glycemic control and avoid accompanying risks of hypoglycemia

Content Provider	PubMed Central
Author	Gao, Jialin Xiong, Qianyin Miao, Jun Zhang, Yao Xia, Libing Lu, Meiqin Zhang, Binhua Chen, Yueping Zhang, Ansu Cui, Yu Wang, Li-zhuo
Copyright Year	2015
Abstract	The aims of the present study were to explore the efficacy of glycemic control and the risks of hypoglycemia with different methods of insulin therapy, and to provide reference data for the clinical treatment of diabetes. In this retrospective study, hospitalized patients diagnosed with type 2 diabetes between March and December 2014, in the Department of Endocrinology in the First Affiliated Hospital of Wannan Medical College, were divided into three groups, including an intensive insulin analogue therapy group, a premixed insulin analogue treatment group and a premixed human insulin therapy group. The efficacy of glycemic control and the incidence of hypoglycemia were determined in each of the insulin treatment groups. Compared with the other treatment groups, the intensive insulin analogue therapy group was associated with superior blood glucose control, shorter time to reach standard insulin regimen, shorter hospitalization time, fewer fluctuations in blood glucose levels and lower insulin dosage on discharge from hospital. However, this treatment was also associated with a high risk of hypoglycemia. In conclusion, when combined with the effective prevention of hypoglycemia and appropriate nursing care (especially in hospital care), intensive insulin analogue therapy may provide the greatest benefit to patients.
Related Links	http://dx.doi.org/10.3892/br.2015.434
Ending Page	288
Page Count	5
Starting Page	284
File Format	PDF
ISSN	20499442
e-ISSN	20499442
Journal	Biomedical Reports
Issue Number	3
Volume Number	3
Language	English
Publisher	D.A. Spandidos
Publisher Date	2015-05-01
Access Restriction	Open
Rights Holder	D.A. Spandidos
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Neuroscience Medicine Biochemistry, Genetics and Molecular Biology Pharmacology, Toxicology and Pharmaceutics

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