NDLI: Prenatal Maternal and Possible Transgenerational Epigenetic Effects on Milk Production

Content Provider	PubMed Central
Author	Gudex, Boyd Johnson, David Singh, Kuljeet
Editor	Barendse, William
Copyright Year	2014
Abstract	This study investigated whether the prenatal maternal environment in dairy cattle influences the postnatal milking performance of the resulting daughters and grand-daughters. Linear mixed models were used to analyse whole season milk production from ∼46000 Jersey and ∼123000 Holstein Friesian cows in their 1st and 2nd lactations. Variation in the prenatal environment was associated with a small but significant (P<0.05) proportion of the total phenotypic variation (0.010 to 0.015) in all traits in Holstein Friesian cows and in the first lactation milk volume (0.011) and milk protein (0.011), and the second lactation milk fat (0.015) in the Jersey breed. This indicates that the prenatal environment does influence the adult performance of the subsequent daughter. Associations between daughter performance and dam and grand-dam traits indicative of their prenatal environment were also estimated. A one litre increase in the dam’s herd test milk volume was associated with a 7.5 litre increase in the daughters’ whole season milk yield and a 1% increase in either the dams’ herd test milk fat or protein percentage was associated with a reduction in daughter whole season milk volume (−49.6 and −45.0 litres for dam fat and protein, respectively). Similar results between the grand-dam herd test traits ansd the daughters’ whole season milk production were observed with a 1% increase in either grand-dam milk fat or protein percentage associated with a reduction in daughter whole season milk yield (−34.7 and −9.7 litres for fat and protein, respectively). This study revealed that the prenatal environment of the dam and the grand-dam can influence milk production in the subsequent daughters, though the effects are small. The similarity of the results between the dam daughter and the grand-dam daughter analyses suggests that the majority of the prenatal maternal effects are mediated by epigenetic mechanisms.
Related Links	http://dx.doi.org/10.1371/journal.pone.0098928
Starting Page	98928
File Format	PDF
ISSN	19326203
e-ISSN	19326203
Journal	PLoS ONE
Issue Number	6
Volume Number	9
Language	English
Publisher	Public Library of Science
Publisher Date	2014-06-01
Access Restriction	Open
Rights Holder	Public Library of Science
Subject Keyword	Biochemistry, Genetics and Molecular Biology(all) Agricultural and Biological Sciences(all) Medicine(all) Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Investigations on Transgenerational Epigenetic Response Down the Male Line in F2 Pigs

Transgenerational Epigenetic Programming of the Brain Transcriptome and Anxiety Behavior

Epigenetic Effects of Prenatal Stress on 11β-Hydroxysteroid Dehydrogenase-2 in the Placenta and Fetal Brain

Identification of Genomic Features in Environmentally Induced Epigenetic Transgenerational Inherited Sperm Epimutations

Noninvasive Prenatal Molecular Karyotyping from Maternal Plasma

Transgenerational Actions of Environmental Compounds on Reproductive Disease and Identification of Epigenetic Biomarkers of Ancestral Exposures

Dioxin (TCDD) Induces Epigenetic Transgenerational Inheritance of Adult Onset Disease and Sperm Epimutations

The Mechanism of Environmental Endocrine Disruptors (DEHP) Induces Epigenetic Transgenerational Inheritance of Cryptorchidism

Transgenerational Effects of Stress Exposure on Offspring Phenotypes in Apomictic Dandelion

Prenatal Maternal and Possible Transgenerational Epigenetic Effects on Milk Production

Similar Documents

Investigations on Transgenerational Epigenetic Response Down the Male Line in F2 Pigs

Transgenerational Epigenetic Programming of the Brain Transcriptome and Anxiety Behavior

Epigenetic Effects of Prenatal Stress on 11β-Hydroxysteroid Dehydrogenase-2 in the Placenta and Fetal Brain

Identification of Genomic Features in Environmentally Induced Epigenetic Transgenerational Inherited Sperm Epimutations

Noninvasive Prenatal Molecular Karyotyping from Maternal Plasma

Transgenerational Actions of Environmental Compounds on Reproductive Disease and Identification of Epigenetic Biomarkers of Ancestral Exposures

Dioxin (TCDD) Induces Epigenetic Transgenerational Inheritance of Adult Onset Disease and Sperm Epimutations

The Mechanism of Environmental Endocrine Disruptors (DEHP) Induces Epigenetic Transgenerational Inheritance of Cryptorchidism

Transgenerational Effects of Stress Exposure on Offspring Phenotypes in Apomictic Dandelion

Prenatal Maternal and Possible Transgenerational Epigenetic Effects on Milk Production