NDLI: Phthalate Levels in Cord Blood Are Associated with Preterm Delivery and Fetal Growth Parameters in Chinese Women

Content Provider	PubMed Central
Author	Huang, Yujing Li, Junnan Garcia, Jose M. Lin, Hui Wang, Yanzhou Yan, Ping Wang, Lingqiao Tan, Yao Luo, Jiaohua Qiu, Zhiqun Chen, Ji-an Shu, Weiqun
Editor	Chen, Aimin
Copyright Year	2014
Abstract	Data concerning the effects of phthalate exposure on preterm delivery and fetal growth are limited in humans. In this paper, we assessed the relationship between 15 phthalate levels in cord blood and preterm delivery and fetal growth parameters in 207 Chinese women going into labor. Exposure to phthalates except DCHP was associated with gestational age reduction and preterm delivery (p<0.05). There were associations between phthalates and fetal growth parameters, many of which disappeared when analyses were adjusted for gestational age, especially in male infants (Only DEEP was associated with birth weight; DEP, DNHP, BBP, DNP with abdominal circumference; DEP, DBP, DCHP, DEHP with femur length in female infants. And DPP, DBEP was associated with birth length in male infants. p<0.05). This study indicates that prenatal exposure to phthalates is associated with younger gestational age and preterm delivery. Also, phthalate exposure may adversely affect fetal growth parameters via gestational age reduction and preterm delivery with a significant gender effect.
Related Links	http://dx.doi.org/10.1371/journal.pone.0087430
Starting Page	87430
File Format	PDF
ISSN	19326203
e-ISSN	19326203
Journal	PLoS ONE
Issue Number	2
Volume Number	9
Language	English
Publisher	Public Library of Science
Publisher Date	2014-02-01
Access Restriction	Open
Rights Holder	Public Library of Science
Subject Keyword	Biochemistry, Genetics and Molecular Biology(all) Agricultural and Biological Sciences(all) Medicine(all) Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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