NDLI: Bioactive scaffolds for engineering vascularized cardiac tissues

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Bioactive scaffolds for engineering vascularized cardiac tissues

Content Provider	PubMed Central
Author	Chiu, Loraine Radisic, Milica Vunjak-novakovic, Gordana
Abstract	Functional vascularization is a key requirement for the development and function of most tissues, and most critically cardiac muscle. Rapid and irreversible loss of cardiomyocytes during cardiac infarction directly results from the lack of blood supply. Contractile cardiac grafts, engineered using cardiovascular cells in conjunction with biomaterial scaffolds, are an actively studied method for cardiac repair. In this article, we focus on biomaterial scaffolds designed to mediate the development and maturation of vascular networks, by immobilized growth factors. The interactive effects of multiple vasculogenic factors are discussed in the context of cardiac tissue engineering.
Related Links	http://dx.doi.org/10.1002/mabi.201000202
Ending Page	1301
Page Count	16
Starting Page	1286
File Format	PDF
ISSN	16165187
e-ISSN	16165195
Journal	Macromolecular bioscience
Issue Number	11
Volume Number	10
Language	English
Publisher Date	2010-11-10
Access Restriction	Open
Subject Keyword	Biotechnology Materials Chemistry Bioengineering Polymers and Plastics Biomaterials Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Materials Chemistry Biomaterials Bioengineering Biotechnology Polymers and Plastics

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