NDLI: Fabrication of Nanofiber Scaffolds with Gradations in Fiber Organization and Their Potential Applications

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Fabrication of Nanofiber Scaffolds with Gradations in Fiber Organization and Their Potential Applications

Content Provider	PubMed Central
Author	Xie, Jingwei Ma, Bing Michael, Praveesuda Lorwattanapongsa Shuler, Franklin D.
Abstract	A new and simple method for fabrication of nanofiber scaffolds with gradations in fiber organization is reported. The nanofiber organization, achieved by deposition of random fibers on the uniaxially-aligned nanofiber mat in a gradient manner, directed morphological changes of applied adipose-derived stem cells. These morphological changes and resultant biochemical changes can help mimic the structural orientation of complex biomechanical structures like the collagen fiber structure at the tendon-to-bone insertion site. In addition, chemical gradients can be established through nanoencapsulation in this novel scaffold allowing for enhanced biomedical applications.
Related Links	http://dx.doi.org/10.1002/mabi.201200115
Ending Page	1341
Page Count	6
Starting Page	1336
File Format	PDF
ISSN	16165187
e-ISSN	16165195
Journal	Macromolecular bioscience
Issue Number	10
Volume Number	12
Language	English
Publisher Date	2012-10-01
Access Restriction	Open
Subject Keyword	Biotechnology Materials Chemistry Bioengineering Polymers and Plastics Biomaterials Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Materials Chemistry Biomaterials Bioengineering Biotechnology Polymers and Plastics

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