NDLI: Task-Induced Deactivation from Rest Extends beyond the Default Mode Brain Network

Content Provider	PubMed Central
Author	Harrison, Ben J. Pujol, Jesus Oren, Contreras-rodríguez Carles, Soriano-mas Marina, López-solà Deus, Joan Ortiz, Hector Laura, Blanco-hinojo Alonso, Pino Rosa, Hernández-ribas Cardoner, Narcís Menchón, José M.
Editor	García, Antonio Verdejo
Copyright Year	2011
Abstract	Activity decreases, or deactivations, of midline and parietal cortical brain regions are routinely observed in human functional neuroimaging studies that compare periods of task-based cognitive performance with passive states, such as rest. It is now widely held that such task-induced deactivations index a highly organized ‘default-mode network’ (DMN): a large-scale brain system whose discovery has had broad implications in the study of human brain function and behavior. In this work, we show that common task-induced deactivations from rest also occur outside of the DMN as a function of increased task demand. Fifty healthy adult subjects performed two distinct functional magnetic resonance imaging tasks that were designed to reliably map deactivations from a resting baseline. As primary findings, increases in task demand consistently modulated the regional anatomy of DMN deactivation. At high levels of task demand, robust deactivation was observed in non-DMN regions, most notably, the posterior insular cortex. Deactivation of this region was directly implicated in a performance-based analysis of experienced task difficulty. Together, these findings suggest that task-induced deactivations from rest are not limited to the DMN and extend to brain regions typically associated with integrative sensory and interoceptive processes.
Related Links	http://dx.doi.org/10.1371/journal.pone.0022964
Starting Page	22964
File Format	PDF
ISSN	19326203
e-ISSN	19326203
Journal	PLoS ONE
Issue Number	7
Volume Number	6
Language	English
Publisher	Public Library of Science
Publisher Date	2011-07-01
Access Restriction	Open
Rights Holder	Public Library of Science
Subject Keyword	Biochemistry, Genetics and Molecular Biology(all) Agricultural and Biological Sciences(all) Medicine(all) Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Task-Induced Deactivation from Rest Extends beyond the Default Mode Brain Network

Differential Deactivation during Mentalizing and Classification of Autism Based on Default Mode Network Connectivity

Deactivation of the Default Mode Network as a Marker of Impaired Consciousness: An fMRI Study

Dopamine Transporters in Striatum Correlate with Deactivation in the Default Mode Network during Visuospatial Attention

Abnormal Brain Default-Mode Network Functional Connectivity in Drug Addicts

The Default Mode Network and the Working Memory Network Are Not Anti-Correlated during All Phases of a Working Memory Task

Default Mode Network Connectivity in Stroke Patients

Functional imaging evidence for task-induced deactivation and disconnection of a major default mode network hub in the mouse brain

Default-Mode-Like Network Activation in Awake Rodents

Task-Induced Deactivation from Rest Extends beyond the Default Mode Brain Network

Similar Documents

Task-Induced Deactivation from Rest Extends beyond the Default Mode Brain Network

Differential Deactivation during Mentalizing and Classification of Autism Based on Default Mode Network Connectivity

Deactivation of the Default Mode Network as a Marker of Impaired Consciousness: An fMRI Study

Dopamine Transporters in Striatum Correlate with Deactivation in the Default Mode Network during Visuospatial Attention

Abnormal Brain Default-Mode Network Functional Connectivity in Drug Addicts

The Default Mode Network and the Working Memory Network Are Not Anti-Correlated during All Phases of a Working Memory Task

Default Mode Network Connectivity in Stroke Patients

Functional imaging evidence for task-induced deactivation and disconnection of a major default mode network hub in the mouse brain

Default-Mode-Like Network Activation in Awake Rodents

Task-Induced Deactivation from Rest Extends beyond the Default Mode Brain Network