NDLI: Noninvasive assessment of the developing Xenopus cardiovascular system using optical coherence tomography

Content Provider	PubMed Central
Author	Boppart, Stephen A. Tearney, Gary J. Bouma, Brett E. Southern, James F. Brezinski, Mark E. Fujimoto, James G.
Copyright Year	1997
Abstract	Studies investigating normal and abnormal cardiac development are frequently limited by an inability to assess cardiovascular function within the intact organism. In this work, optical coherence tomography (OCT), a new method of micron-scale, noninvasive imaging based on the measurement of backscattered infrared light, was introduced for the high resolution assessment of structure and function in the developing Xenopus laevis cardiovascular system. Microstructural details, such as ventricular size and wall positions, were delineated with OCT at 16-μm resolution and correlated with histology. Three-dimensional representation of the cardiovascular system also was achieved by repeated cross-sectional imaging at intervals of 25 μm. In addition to structural information, OCT provides high speed in vivo axial ranging and imaging, allowing quantitative dynamic activity, such as ventricular ejection fraction, to be assessed. The sensitivity of OCT for dynamic assessment was demonstrated with an inotropic agent that altered cardiac function and dimensions. Optical coherence tomography is an attractive new technology for assessing cardiovascular development because of its high resolution, its ability to image through nontransparent structures, and its inexpensive portable design. In vivo and in vitro imaging are performed at a resolution approaching that of histopathology without the need for animal killing.
Starting Page	4256
File Format	PDF
ISSN	10916490
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	9
Volume Number	94
Language	English
Publisher	The National Academy of Sciences of the USA
Publisher Date	1997-04-29
Access Restriction	Open
Rights Holder	The National Academy of Sciences of the USA
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Noninvasive assessment of the developing Xenopus cardiovascular system using optical coherence tomography.

Noninvasive, In Vivo Assessment of Mouse Retinal Structure Using Optical Coherence Tomography

Preliminary Results of Noninvasive Ocular Rigidity in Diabetic Retinopathy Using Optical Coherence Tomography

Optical Coherence Tomography of the Larynx Using the Niris System

Using optical coherence tomography for the longitudinal noninvasive evaluation of epidermal thickness in a murine model of chronic skin inflammation

Assessment of fractional flow reserve in intermediate coronary stenosis using optical coherence tomography-based machine learning

Assessment of Coronary Plaque Vulnerability with Optical Coherence Tomography

Noninvasive Imaging of Retinal Morphology and Microvasculature in Obese Mice Using Optical Coherence Tomography and Optical Microangiography

Optical coherence tomography using the Niris system in otolaryngology

Noninvasive assessment of the developing Xenopus cardiovascular system using optical coherence tomography

Similar Documents

Noninvasive assessment of the developing Xenopus cardiovascular system using optical coherence tomography.

Noninvasive, In Vivo Assessment of Mouse Retinal Structure Using Optical Coherence Tomography

Preliminary Results of Noninvasive Ocular Rigidity in Diabetic Retinopathy Using Optical Coherence Tomography

Optical Coherence Tomography of the Larynx Using the Niris System

Using optical coherence tomography for the longitudinal noninvasive evaluation of epidermal thickness in a murine model of chronic skin inflammation

Assessment of fractional flow reserve in intermediate coronary stenosis using optical coherence tomography-based machine learning

Assessment of Coronary Plaque Vulnerability with Optical Coherence Tomography

Noninvasive Imaging of Retinal Morphology and Microvasculature in Obese Mice Using Optical Coherence Tomography and Optical Microangiography

Optical coherence tomography using the Niris system in otolaryngology

Noninvasive assessment of the developing Xenopus cardiovascular system using optical coherence tomography