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Asymmetric Synthesis of Tetrasubstituted α-Aminophosphonic Acid Derivatives
| Content Provider | MDPI |
|---|---|
| Author | Adri, án López-Francés Maestro, Aitor Corte, Xabier del de Marigorta, Edorta Martínez Palacios, Francisco Vicario, Javier |
| Copyright Year | 2021 |
| Description | Due to their structural similarity with natural α-amino acids, α-aminophosphonic acid derivatives are known biologically active molecules. In view of the relevance of tetrasubstituted carbons in nature and medicine and the strong dependence of the biological activity of chiral molecules into their absolute configuration, the synthesis of α-aminophosphonates bearing tetrasubstituted carbons in an asymmetric fashion has grown in interest in the past few decades. In the following lines, the existing literatures for the synthesis of optically active tetrasubstituted α-aminophosphonates are summarized, comprising diastereoselective and enantioselective approaches. |
| Starting Page | 3202 |
| e-ISSN | 14203049 |
| DOI | 10.3390/molecules26113202 |
| Journal | Molecules |
| Issue Number | 11 |
| Volume Number | 26 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-05-27 |
| Access Restriction | Open |
| Subject Keyword | Molecules Organic Chemistry Asymmetric Synthesis Α-aminophosphonic Acid Tetrasubstituted Carbons Diastereoselective Enantioselective Α-aminophosphonates |
| Content Type | Text |
| Resource Type | Article |
