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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Dutta, A. Dutta, A. |
| Copyright Year | 2013 |
| Description | Author affiliation: Charite - Universitatsmed. Berlin, Berlin, Germany (Dutta, A.) || Gnan Syst. LLP, Kolkata, India (Dutta, A.) |
| Abstract | Non-invasive brain stimulation (NIBS) involves passing low currents through the brain where detectable effects on neuronal activity and cognitive function have been found due to small but effective voltage gradients brought about in the brain tissue. Although NIBS is a promising tool for inducing alteration of cortical excitability but it presents challenge in terms of optimization of the electrode placement and stimulation parameters, especially in cases of heterogeneously damaged cortical structures where getting accurate conductivity values for computational head-modeling is challenging. Moreover, the target in the brain for NIBS to facilitate a specific residual function may be unknown where electroencephalogram (EEG) source localization for related event related potential may play an important role. Therefore, in this theoretical study, we explored the possibility of using a lead-field based formulation of the electromagnetic reciprocity theorem to reciprocally energize the EEG electrodes in order to target the neural source of event related potentials during a functional task. Moreover, a Magnetic Resonance Current Density Imaging based method is proposed to determine subject-specific lead-field where it is postulated that such NIBS-based artificial subthreshold ephaptic feedback may facilitate cortical neural events (e.g., event related synchronization/desynchronization), which remains to be validated in future via human studies. |
| Starting Page | 447 |
| Ending Page | 451 |
| File Size | 628363 |
| Page Count | 5 |
| File Format | |
| ISBN | 9781467319690 |
| ISSN | 19483554 |
| DOI | 10.1109/NER.2013.6695968 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2013-11-06 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Electric potential Brain Lead Conductivity Electroencephalography Extracellular Equations |
| Content Type | Text |
| Resource Type | Article |
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