NDLI: Performance of fluorescence molecular tomography with hybrid diffuse optical tomography guidance and normalized born method

Content Provider	IEEE Xplore Digital Library
Author	Daifa Wang Ling Wang Yubo Fan Deyu Li
Copyright Year	2011
Description	Author affiliation: School of Biological Science and Medical Engineering, Beihang University, Beijing, China, 100191 (Ling Wang; Yubo Fan; Deyu Li) \|\| State Key Laboratory of Software Development Environment, Beihang University, Beijing, China, 100191 (Daifa Wang)
Abstract	The image quality of fluorescence molecular tomography (FMT) can be significantly improved with diffuse optical tomography (DOT) guidance, by incorporating the prior optical properties information recovered from DOT into its forward photon propagation model. Although present studies all assume that the absolute transmitted excitation light intensity can be measured for DOT, the hypothesis doesn't hold for most cases, because some extent of deviation in the calibrated excitation light amplification factor is inevitable in a non-laboratory (i.e., in vivo) imaging environment. In this paper, we evaluate the impact on FMT reconstruction accuracy of the use of hybrid DOT guidance and normalized born method. Results demonstrate that the quantification ability of FMT with DOT guidance alone varies greatly as the absolute deviation in excitation light amplification factor increases. In contrast, the hybrid method investigated is robust to the deviations, suggesting that the hybrid of DOT guidance and normalized born method is essential for quantitative FMT in complex in vivo conditions.
Starting Page	434
Ending Page	438
File Size	497073
Page Count	5
File Format	PDF
ISBN	9781424493517
e-ISBN	9781424493524
DOI	10.1109/BMEI.2011.6098340
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-10-15
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Biomedical optical imaging heterogeneous media diffuse optical tomography normalized born method US Department of Transportation Fluorescence Optical imaging Adaptive optics fluoescence molecular tomography Optical scattering Image reconstruction
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in