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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Liu, J.L. Qian, Y. Itatani, K. Murakami, A. Shiurba, R. Miyaji, K. Miyakoshi, T. Umezu, M. |
| Copyright Year | 2011 |
| Description | Author affiliation: Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (Qian, Y.; Miyaji, K.) || Australian School of Advanced Medicine, Macquarie University, Sydney, Australia (Shiurba, R.) || School of Medicine, Kitasato University, Kanagawa, Japan (Miyakoshi, T.) || Center for Advanced Biomedical Sciences, TWIns, Waseda University, Tokyo, Japan (Liu, J.L.; Itatani, K.; Murakami, A.; Umezu, M.) |
| Abstract | Currently, few applications of computational hemodynamics predict outcomes after palliative surgery for congenital heart defects such as hypolastic left heart syndrome in infants. Here, we report on three-dimensional imaging methods for modeling recoarctation that commonly occurs in the distal aortic arch following the Norwood procedure. We used computer-aided design to simulate seven stages of increasing stenosis, analyze the resulting hemodynamics, and visualize the impairment of blood flow. A disproportionate drop in pressure occurred when stenosis reached 20% of the cross-sectional area of the descending aorta. The corresponding decrease in blood flow in the descending aorta was relatively small, however. Accordingly our findings suggest a reasonable approach to this phenomenon is watchful waiting rather than immediate surgical intervention. Such patient-specific predictions appear to be valuable for minimizing the risks of corrective surgery. These methods also may be applied to procedures for alleviating other congenital heart defects. |
| Starting Page | 318 |
| Ending Page | 323 |
| File Size | 1139792 |
| Page Count | 6 |
| File Format | |
| ISBN | 9781424493517 |
| e-ISBN | 9781424493524 |
| DOI | 10.1109/BMEI.2011.6098269 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2011-10-15 |
| Publisher Place | China |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | recoarctation Solid modeling computational fluid dynamics computer-aided design hemodynamics Geometry Norwood procedure Surgery Three dimensional displays Numerical models Hemodynamics medical imaging Biomedical imaging |
| Content Type | Text |
| Resource Type | Article |
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