NDLI: Bioinformatics analysis and characteristics of glycoprotein G encoded by the newly identified Us4 gene of duck enteritis virus

Content Provider	IEEE Xplore Digital Library
Author	Xiaoyuan Yang Anchun Cheng Mingshu Wang Dekang Zhu Xiaoyue Chen Renyong Jia Qihui Luo Yi Zhou Zhengli Chen
Copyright Year	2010
Description	Author affiliation: Key laboratory of Animal Disease and Human Health of Sichuan Province, Ya'an, 625014, China (Renyong Jia; Qihui Luo; Yi Zhou; Zhengli Chen) \|\| Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Ya'an, 625014, China (Xiaoyuan Yang; Anchun Cheng; Mingshu Wang; Dekang Zhu; Xiaoyue Chen)
Abstract	The US4 open reading frame of the Duck enteritis virus (DEV) encodes glycoprotein G, a protein comprising 459 amino acids with a putative molecular mass of 50.58 kDa. The characteristics of this protein were analyzed through bioinformatics softwares and tools. Glycoprotein G sequence analysis indicates that the protein possesses typical characteristics of membrane glycoproteins containing two transmembrane domains and a N-terminal hydrophobic signal peptide sequence. Through secondary structure presumption, gG consists of extended strand (E) with 28.54% and random coil (C) with 44.23%, in contrast, alpha helix (H) with 16.99% and beta turn (T) with 10.24%, suggesting that DEV-gG has more noncohesive flexibility structures, which always contain B cell dominant epitopes. Furthermore, the result of estimating potential antigenic epitopes shows that gG contains 18 antigenic determinants locating the whole sequence. These results indicate that DEV-gG has good immunogenicity. In conclusion, all the data and consequences will provide a basis for further functional study of DEV-glycoprotein G and provide rational data for the development of new antibodies and immunoassays in the clinical diagnosis of DEV.
Starting Page	2159
Ending Page	2164
File Size	571394
Page Count	6
File Format	PDF
ISBN	9781424464951
e-ISBN	9781424464982
DOI	10.1109/BMEI.2010.5639299
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-10-16
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Proteins Function Duck Enteritis Virus Peptides Amino acids Biomembranes Structure Bioinformatics Glycoprotein G Immune system Diseases
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Bioinformatics Analysis and Characteristics of Glycoprotein K Encoded by the Newly Identified UL53 Gene of Duck Enteritis Virus

Molecular cloning and sequence analysis of the duck enteritis virus Us4 gene

Bioinformatics Analysis and Characteristics of Us2 protein Encoded by the Newly Identified US2 Gene of Duck Enteritis Virus

Molecular cloning and characterization of the newly identified gC gene of duck plague virus

Bioinformatics Analysis of UL41 Protein Encoded by UL41 Gene of Duck Plague Virus

Molecular Cloning and Characterization of the UL10 Gene from Duck Enteritis Virus

Molecular Characterization Analysis of Newly Identified Duck Enteritis Virus UL55 Gene

Molecular Cloning and Sequence Analysis of the Duck Plague Virus gI Gene

Characterization of codon usage bias in the gI gene of duck enteritis virus

Bioinformatics analysis and characteristics of glycoprotein G encoded by the newly identified Us4 gene of duck enteritis virus

Similar Documents

Bioinformatics Analysis and Characteristics of Glycoprotein K Encoded by the Newly Identified UL53 Gene of Duck Enteritis Virus

Molecular cloning and sequence analysis of the duck enteritis virus Us4 gene

Bioinformatics Analysis and Characteristics of Us2 protein Encoded by the Newly Identified US2 Gene of Duck Enteritis Virus

Molecular cloning and characterization of the newly identified gC gene of duck plague virus

Bioinformatics Analysis of UL41 Protein Encoded by UL41 Gene of Duck Plague Virus

Molecular Cloning and Characterization of the UL10 Gene from Duck Enteritis Virus

Molecular Characterization Analysis of Newly Identified Duck Enteritis Virus UL55 Gene

Molecular Cloning and Sequence Analysis of the Duck Plague Virus gI Gene

Characterization of codon usage bias in the gI gene of duck enteritis virus

Bioinformatics analysis and characteristics of glycoprotein G encoded by the newly identified Us4 gene of duck enteritis virus