NDLI: Detection of Electrical Activity of Pancreatic Beta-cells Using Micro-electrode Arrays

Content Provider	IEEE Xplore Digital Library
Author	Bornat, Y. Raoux, M. Boutaib, Y. Morin, F. Charpentier, G. Lang, J. Renaud, S.
Copyright Year	2010
Abstract	In this position paper we propose a new approach to provide online in-vivo recordings of organ activity in real time and to overcome three major shortcuts of currently used invasive glucose sensors. In the context of diabetes, standard glucosensors recognize only glucose, whereas circulating lipids as well as amino acids are known to increase the demand in insulin and, under physiological circumstances, its secretion. Furthermore, the integration of other relevant signals such as hormones provides a clear advantage. Consequently, using the β-cell as a signal integrator combined with ASIC technology ensures a physiological signal and its read-out in real time thus avoiding complex algorithms. We describe a closed-loop architecture for exploiting those bio-sensors and potentially able to provide a control feedback for real-time insulin delivery.
Starting Page	233
Ending Page	236
File Size	422757
Page Count	4
File Format	PDF
ISBN	9780769539782
e-ISBN	9781424460267
DOI	10.1109/DELTA.2010.60
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-01-13
Publisher Place	Vietnam
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Closed-loop insulin delivery Fluids and secretions Lipidomics Amino acids Biochemistry Insulin Micro-electrode arrays Application specific integrated circuits Feedback Diabetes Pancreas Biosensors Sugar
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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