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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Zhang-Zhi Hu Cohen, K.B. Hirschman, L. Valencia, A. Hongfang Liu Giglio, M.G. Wu, C.H. |
| Copyright Year | 2008 |
| Description | Author affiliation: Protein Inf. Resource, Georgetown Univ. Med. Center, Washington, DC (Zhang-Zhi Hu; Wu, C.H.) || Spanish Nat. Cancer Res. Centre (CNIO) (Valencia, A.) || Inf. Technol. Center, MITRE Corp., MA (Cohen, K.B.; Hirschman, L.) || Dept. of Biostat., Biomath. & Bioinf., Georgetown Univ. Med. Center, Washington, DC (Hongfang Liu) || Sch. of Med., Univ. of Maryland, Baltimore, MD (Giglio, M.G.) |
| Abstract | The ever-increasing scientific literature and the exponential growth of large-scale molecular data have prompted active research in biological text mining to facilitate literature-based curation of molecular databases. Meanwhile, systems biology and bio-ontologies are emerging as critical tools in biological research where complex data in disparate resources are generated, integrated and analyzed. Both rely on literature for data annotation and analysis. The challenges facing us are to develop broadly utilized text mining tools and systems, and to bring together developer and user communities for system development and evaluation. We describe a framework for linking text mining tools with ontology and systems biology, extending from a previously developed text mining resource, iProLINK. We focus on molecular and ontological resources, including genes/proteins, protein-protein interaction (PPI), and Protein Ontology. The framework consists of two major components: a user interface for text mining of PPI from an integrated tool server and software modules to allow text mining outputs to be created, ranked, and used by the community. Use cases are presented for assessing the gaps and making recommendations for future development. |
| Starting Page | 467 |
| Ending Page | 472 |
| File Size | 1415353 |
| Page Count | 6 |
| File Format | |
| ISBN | 9780769534527 |
| DOI | 10.1109/BIBM.2008.73 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2008-11-03 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Text mining systems biology Data analysis Ontologies protein network Proteins Databases Systems biology User interfaces community workshop text mining protein-protein interaction Large-scale systems Joining processes Software tools ontology |
| Content Type | Text |
| Resource Type | Article |
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