NDLI: Images Based System for Surface Matching in Macromolecular Screening

Content Provider	IEEE Xplore Digital Library
Author	Merelli, I. Cozzi, P. D'Agostino, D. Cleamatis, A. Milanesi, L.
Copyright Year	2008
Description	Author affiliation: Inst. for Biomed. Technol., Nat. Res. Council, Milan (Merelli, I.; Cozzi, P.; Milanesi, L.) \|\| Inst. for Appl. Math. & Inf. Technol., Nat. Res. Council, Genoa (D'Agostino, D.; Cleamatis, A.)
Abstract	Computer vision technologies of structure matching based on surface representation have demonstrated their effectiveness in many research fields. In particular they can be successfully applied to in silico studies of molecular biology. Protein activities, in fact, are driven by their external characteristics, therefore the ability to match surfaces allows one to quickly infer information about possible interactions and functions of biological components.In this work we present a surface matching algorithm which is able to screen possible macromolecular interactions in terms of surface complementarities. The main characteristics of the algorithm is the exploitation of an intermediate level of data representation for 3D surfaces based on images of local description. This approach enables the matching of small pieces of surfaces, which is a crucial aspect when working in the biological context.
Starting Page	397
Ending Page	401
File Size	282837
Page Count	5
File Format	PDF
ISBN	9780769534527
DOI	10.1109/BIBM.2008.20
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-11-03
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Proteins Art Councils Surface morphology Clustering algorithms Mathematics Space exploration Bioinformatics Information technology Information analysis
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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