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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Shin-Yuan Su Che-Chou Shen Chih-Kuang Yeh |
| Copyright Year | 2008 |
| Description | Author affiliation: Dept. of Biomed. Eng. & Environ. Sci., Nat. Tsing Hua Univ., Hsinchu (Shin-Yuan Su; Chih-Kuang Yeh) || Dept. of Electr. Eng., Nat. Taiwan Univ. of Sci. & Technol., Taipei (Che-Chou Shen) |
| Abstract | Detection of ultrasound contrast agents (UCAs) based on their nonlinear characteristics are popular for imaging blood perfusion. For microcirculation imaging, a higher frequency system (>10 MHz) is required to obtain higher spatial resolution. However, high-frequency nonlinear techniques usually suffer from insufficient signal-to-noise ratio (SNR) due to the intense attenuation and the limited resonance frequency of commercial UCAs. In this study, the proposed dual-frequency excitation method involves the simultaneous transmission of two high-frequency sinusoids to produce an envelope signal at the difference frequency, which provides the low-frequency driving force for UCAs nonlinear oscillation. The low-frequency envelope results in significant improvement in contrast-to-tissue ratio (CTR) while the high-frequency carrier signal provides the fine image resolution. Moreover, the destruction efficiency with high-frequency ultrasound also improves. The destruction threshold of UCAs with dual-frequency excitation is generally reduced as compared to the conventional tone burst. |
| Starting Page | 1631 |
| Ending Page | 1634 |
| File Size | 2085144 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424424283 |
| DOI | 10.1109/ULTSYM.2008.0398 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2008-11-02 |
| Publisher Place | China |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Ultrasonic imaging Blood High-resolution imaging Amplitude modulation Resonance Pulse modulation Biomedical imaging Spatial resolution Resonant frequency Frequency estimation dual-frequency excitation ultrasound contrast agents high-frequency |
| Content Type | Text |
| Resource Type | Article |
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