NDLI: A high frequency continuous-wave Doppler ultrasound system for detection of blood flow in the microcirculation

Content Provider	IEEE Xplore Digital Library
Author	Christopher, D.A. Burns, P.N. Armstrong, J. Foster, F.S.
Copyright Year	1995
Description	Author affiliation: Dept. of Med. Biophys., Toronto Univ., Ont., Canada (Christopher, D.A.)
Abstract	Basic ultrasound physics and several clinical and experimental observations suggest that high frequency Doppler ultrasound (HFD) operating in the frequency range 20 to 100 MHz holds the promise of a real-time, non-invasive, depth-resolving technique capable of detecting blood flow in the microcirculation with suitable spatial and temporal resolutions. This paper describes a directional, continuous-wave, high frequency Doppler ultrasound (CW HFD) system which we have developed and optimised for use in an investigation to quantify HFD's abilities. The system electronics operates over the frequency range 1 to 200 MHz and has a dynamic range of 100 dB and a noise floor of 10 nV. Using a string phantom and a sensitive 40 MHz transducer we show that HFD can detect and measure velocities of the order of 1 mm/s, the velocity of blood in a capillary. Also, using in vivo measurements we demonstrate that HFD is sensitive to the detection of blood flow in small vessels.
Starting Page	1493
Ending Page	1496
File Size	291294
Page Count	4
File Format	PDF
ISBN	0780329406
ISSN	10510117
DOI	10.1109/ULTSYM.1995.495838
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1995-11-07
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Frequency Ultrasonic imaging Blood flow Physics Spatial resolution Dynamic range Imaging phantoms Transducers Velocity measurement In vivo
Content Type	Text
Resource Type	Article

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