Please wait, while we are loading the content...
| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Joshi, R.P. Song, J. Kolb, J. Schoenbach, K.H. Gaudet, J. Baum, C. |
| Copyright Year | 2007 |
| Description | Author affiliation: Old Dominion Univ., Norfolk (Joshi, R.P.; Song, J.; Kolb, J.; Schoenbach, K.H.) |
| Abstract | Summary form only given. The use of very high electric fields (~500 kV/cm or higher) with pulse durations in the sub-nanosecond range has been a very recent development in bio-electrics. There appear to be inherent advantages in using short electric pulses such as: (i) negligible thermal heating, (ii) the possibility of selecting the desired time scales through pulse width manipulation, and (iii) the ability to create large trans-membrane potentials across subcellular organelles. This latter can effectively open the way to intra-cellular electromanipulation. The time-dependent transmembrane potential generated across cell membranes can be fashioned by the characteristics of the external excitation. However, at the present time it is not clear what the optimal waveform should be, or the efficiency of generating transmembrane potentials by the ultra-fast, subnanosecond pulses. From a practical standpoint, such excitation typically has "pre-pulses" and oscillatory components. In order to gauge possible bioeffects, an important first step in this subnanosecond arena appears to be theoretical predictions based on modeling. This contribution addresses this aspect. A theoretical analysis has been performed that includes variability m the excitation pulse waveform and details of the dielectric function leading to non-local effects in time. Results on the time-dependent evolution of the transmembrane potential will be presented. Extensions to multiple pulsing and implications for wave-shaping will be discussed. |
| Starting Page | 521 |
| Ending Page | 521 |
| File Size | 44499 |
| Page Count | 1 |
| File Format | |
| ISBN | 9781424409150 |
| ISSN | 07309244 |
| DOI | 10.1109/PPPS.2007.4345827 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2007-06-17 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Voltage Space vector pulse width modulation Bioelectric phenomena Resistance heating Character generation Cells (biology) Biomembranes Pulse generation Predictive models Performance analysis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Atomic and Molecular Physics, and Optics Condensed Matter Physics Electrical and Electronic Engineering |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|