NDLI: Method to minimize dose for CT attenuation correction in SPECT

Content Provider	IEEE Xplore Digital Library
Author	Vija, A.H. Rempel, T.D. Hawman, E.G. Engdahl, J.C.
Copyright Year	2004
Description	Author affiliation: Nucl. Med. Group, Siemens Med. Solutions, Hoffman Estates, IL (Vija, A.H.; Rempel, T.D.; Hawman, E.G.; Engdahl, J.C.)
Abstract	With the recent introduction of hybrid SPECT/CT systems, with diagnostic multi-slice CT (Computed Tomography) capabilities the CT dose delivered to the patient may become an issue, as attenuation compensation in SPECT using co-registered CT data becomes more common in clinical practice. In general, any CT data can be converted to a volume of linear attenuation coefficients (LAC), also referred to as the "attenuation map", or mu-map. We investigated the range of CT settings that minimize the dose to the patient and allow for CT image quality that is appropriate for attenuation correction. SPECT/CT registration issues are outside the scope of this work, and we assume that the objects are perfectly registered. Various phantoms are used to analyze both CT and attenuation-corrected SPECT image quality, where the CT data itself is used to generate the mu-maps. Conclusion: The effective dose to the patient from a CT scan for the purpose of SPECT AC can be lowered to at least 30% to 50% without affecting the image quality of the SPECT AC, using CT derived mu-maps, if an appropriate scan protocol with a very smooth (MTF at 50%: 1.0 Ip/cm) CT reconstruction kernel is used. A further clinical investigation is needed to confirm these findings in clinical practice
Starting Page	2929
Ending Page	2933
File Size	1447187
Page Count	5
File Format	PDF
ISBN	0780387007
ISSN	10823654
e-ISBN	0780387015
DOI	10.1109/NSSMIC.2004.1466300
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-10-16
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Attenuation Computed tomography Image quality Image converters Los Angeles Council Imaging phantoms Image analysis Protocols Image reconstruction Kernel
Content Type	Text
Resource Type	Article

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