NDLI: Study of relative quantification of Tc-99m with partial volume effect and spillover correction for SPECT oncology imaging

Content Provider	IEEE Xplore Digital Library
Author	Boening, G. Protorius, P.H. King, M.A.
Copyright Year	2004
Description	Author affiliation: Dept. of Radiol., Univ. of Massachusetts Med. Sch., Worcester, MA (Boening, G.; Protorius, P.H.; King, M.A.)
Abstract	The apparent concentration of activity in nuclear medicine images is altered by the finite spatial resolution of the imaging systems blurring the counts emitted at a given site out into a surrounding volume in the reconstructed slices. If a structure only partially occupies this volume then more counts will be lost from the location then are brought back in to it from activity within the structure. This is the partial volume effect (PVE). Similarly, counts from surrounding structures can be blurred into the structure. This spillover (SO) also alters the apparent concentration of activity. In total these effects alter the detection and quantification of activity within structures. The increased availability of dual-modality imaging systems whereby high-resolution anatomical information which is registered with the emission slices makes this anatomical information available for use in correcting for the PVE and SO. In this study we investigated the use a template projection-reconstruction method for correction PVE and SO in terms of both its impact of visual image quality and the quantification of activity in simulated spheres of varying contrast relative to a uniform background distribution of activity. We determined that such corrections can dramatically improve both the visualization and quantification of activity within the spheres
Starting Page	2705
Ending Page	2709
File Size	563333
Page Count	5
File Format	PDF
ISBN	0780387007
ISSN	10823654
e-ISBN	0780387015
DOI	10.1109/NSSMIC.2004.1462825
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-10-16
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Oncology Spatial resolution Biomedical imaging Nuclear medicine Back Biomedical engineering Image reconstruction High-resolution imaging Image quality Visualization
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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