NDLI: Preserving Poisson characteristics of PET data with weighted OSEM reconstruction

Content Provider	IEEE Xplore Digital Library
Author	Michel, C. Sibomana, M. Boi, A. Bernard, X. Lonneux, M. Defrise, M. Comtat, C. Kinahan, P.E. Townsend, D.W.
Copyright Year	1999
Description	Author affiliation: PET Lab., Katholieke Univ., Leuven, Belgium (Michel, C.)
Abstract	To evaluate the importance of preserving the Poisson characteristics of PET data when using OSEM reconstruction, the authors have examined several data weighting schemes with increasing complexity which progressively account for attenuation, normalization, random coincidences and Compton scatter with both ordinary and shifted Poisson models. All schemes have first been tested on 2D dynamic data from a decaying phantom filled with H/sub 2//sup 15/O. The images produced by the various weighting schemes were compared to the ones obtained by filtered backprojection reconstruction. Small positive bias (1%) was detected for the FW and SP schemes and may be due to implementation. The impact of these reconstruction methods on physiological parameters is illustrated with clinical protocols measuring myocardial blood flow with /sup 13/NH/sub 3/ and Standard Uptake Values with /sup 18/FDG. Despite the high random rate in cardiac studies, no positive bias was detected in the images when using the AW and ANW schemes with scans precorrected for random and scatter. For whole-body studies, at low random rates, the ANW scheme produced the same quantitative results as the FW and SP ones. That scheme is likely the best choice for obtaining high quality emission images and unbiased ROI's in most situations on current 2D scanners.
Starting Page	1323
Ending Page	1329
File Size	722067
Page Count	7
File Format	PDF
ISBN	0780350219
ISSN	10823654
DOI	10.1109/NSSMIC.1998.774398
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1998-11-08
Publisher Place	Canada
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Image reconstruction Scattering Attenuation Testing Imaging phantoms Reconstruction algorithms Protocols Fluid flow measurement Myocardium
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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