NDLI: Microfluidic device for coincident multi-exposure test on C. elegans

Content Provider	IEEE Xplore Digital Library
Author	Jaehoon Jung Nakajima, M. Takeuchi, M. Qiang Huang Fukuda, T.
Copyright Year	2013
Description	Author affiliation: Inst. for Adv. Res., Nagoya Univ., Nagoya, Japan (Fukuda, T.) \|\| Dept. of Micro-Nano Syst. Eng., Nagoya Univ., Nagoya, Japan (Jaehoon Jung; Takeuchi, M.) \|\| Center for Micro-Nano Mechatron., Nagoya Univ., Nagoya, Japan (Nakajima, M.) \|\| Intell. Robot. Inst., Beijing Inst. of Technol., Beijing, China (Qiang Huang)
Abstract	We developed the microfluidic device to conduct the multi-exposure test with Caenorhabditis elegans (C. elegans) simultaneously. The proposed device has 3 chambers to expose several external stimuli on C. elegans at the same time. Each chamber has a special structure to keep C. elegans inside the chamber; a fixed-geometry check valve and a pillar array. Capacitance was measured to check the effect of external stimulus on C. elegans using a pair of electrodes. To demonstrate the capability of our device, we applied it to multi-exposure test; two heavy metal (Cr and Pb) solutions and K-medium for the control group. Total 21 of young adult stage of C. elegans were divided into three groups and loaded into each chamber for the exposure test. From this experiment, we succeeded to load and keep several worms in each chamber and to check the effect of each solution on C. elegans through the capacitance change measurement. The result indicated that our device was a viable method for the multi-exposure test on C. elegans.
Starting Page	1
Ending Page	4
File Size	425403
Page Count	4
File Format	PDF
e-ISBN	9781479915293
DOI	10.1109/MHS.2013.6710407
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-11-10
Publisher Place	Japan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Microfluidics Metals Capacitance Capacitance measurement Valves Grippers Arrays
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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