NDLI: Biomedical Big Data Analytics for Patient-Centric and Outcome-Driven Precision Health

Content Provider	IEEE Xplore Digital Library
Author	Wang, M.D.
Copyright Year	2015
Description	Author affiliation: Georgia Inst. of Technol., Atlanta, GA, USA (Wang, M.D.)
Abstract	Rapid advancements in biotechnologies such as -omic (genomics, proteomics, metabolomics, lipidomics etc.), next generation sequencing, bio-nanotechnologies, molecular imaging, and mobile sensors etc. accelerate the data explosion in biomedicine and health wellness. Multiple nations around the world have been seeking novel effective ways to make sense of "big data" for evidence-based, outcome-driven, and affordable 5P (Patient-centric, Predictive, Preventive, Personalized, and Precise) healthcare. My main research focus is on multi-modal and multi-scale (i.e. molecular, cellular, whole body, individual, and population) biomedical data analytics for discovery, development, and delivery, including translational bioinformatics in biomarker discovery for personalized care; imaging informatics in histopathology for clinical diagnosis decision support; bionanoinformatics for minimally-invasive image-guided surgery; critical care informatics in ICU for real-time evidence-based decision making; and chronic care informatics for patient-centric health. In this talk, first, I will highlight major challenges in biomedical and health informatics pipeline consisting of data quality control, information feature extraction, advanced knowledge modeling, decision making, and proper action taking through feedback. Second, I will present informatics methodological research in (i) data integrity and integration; (ii) case-based reasoning for individualized care; and (iii) streaming data analytics for real-time decision support using a few mobile health case studies (e.g. Sickle Cell Disease, asthma, pain management, rehabilitation, diabetes etc.). Last, there is big shortage of data scientists and engineers who are capable of handling Big Data. In addition, there is an urgent need to educate healthcare stakeholders (i.e. patients, physicians, payers, and hospitals) on how to tackle these grant challenges. I will discuss efforts such as patient-centric educational intervention, community-based crowd sourcing, and Biomedical Data Analytics MOOC development. Our research has been supported by NIH, NSF, Georgia Research Alliance, Georgia Cancer Coalition, Emory-Georgia Tech Cancer Nanotechnology Center, Children's Health Care of Atlanta, Atlanta Clinical and Translational Science Institute, and industrial partners such as Microsoft Research and HP.
Starting Page	1
Ending Page	2
File Size	192721
Page Count	2
File Format	PDF
ISSN	07303157
e-ISBN	9781467365642
DOI	10.1109/COMPSAC.2015.343
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-07-01
Publisher Place	Taiwan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Biomedical imaging Informatics Bioinformatics Big data Cancer Decision making
Content Type	Text
Resource Type	Article
Subject	Computer Science Applications Software

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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