NDLI: Time-frequency relationships between heart rate and respiration: A diagnosis tool for late onset sepsis in sick premature infants

Content Provider	IEEE Xplore Digital Library
Author	Carrault, G. Beuchee, A. Pladys, P. Senhadji, L. Hernandez, A.
Copyright Year	2009
Description	Author affiliation: Inserm, U642, Rennes, F-35000, France (Carrault, G.; Beuchee, A.; Pladys, P.; Senhadji, L.; Hernandez, A.)
Abstract	The diagnosis of late onset sepsis in premature infants remains difficult because clinical signs are subtle and non-specific and none of the laboratory tests, including CRP and blood culture, have high predictive accuracy. Heart rate variability (HRV) analysis emerges as a promising diagnostic tool. Entropy and long-range fractal correlation are decreased in premature infants with proven sepsis. Besides this, respiration and its relations to HRV appear to be less. The objective of this study was to determine if analysis of time-frequency correlations between the heart rate and respiration amplitude may help for the diagnosis of infection in premature infants. An estimator of the linear relationship between nonstationary signals, recently introduced, is explored. The tests were performed on a cohort study of 60 premature infants. The results show that the correlation in the low frequency band tended to be higher in the sepsis group.
Starting Page	369
Ending Page	372
File Size	173245
Page Count	4
File Format	PDF
ISBN	9781424472819
ISSN	02766547
e-ISBN	9781424472826
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-09-13
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Computers in Cardiology(CinC)
Subject Keyword	Time frequency analysis Heart rate Pediatrics Heart rate variability Testing Laboratories Blood Accuracy Entropy Fractals
Content Type	Text
Resource Type	Article

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