NDLI: Volumetric quantification of myocardial perfusion using analysis of multi-detector computed tomography 3D datasets

Content Provider	IEEE Xplore Digital Library
Author	Kachenoura, N. Veronesi, F. Lodato, J.A. Corsi, C. Mehta, R. Newby, B. Lang, R.M. Mor-Avi, V.
Copyright Year	2009
Description	Author affiliation: University of Chicago, IL, USA (Kachenoura, N.; Lodato, J.A.; Mehta, R.; Newby, B.; Lang, R.M.; Mor-Avi, V.) \|\| DEIS, University of Bologna, Italy (Veronesi, F.; Corsi, C.)
Abstract	Multi-detector computed tomography (MDCT) assessment of myocardial perfusion is based on visualization of 2D slices. To overcome the subjective nature of this analysis, we developed a new technique for quantification of myocardial perfusion from MDCT 3D datasets and tested it against nuclear myocardial perfusion imaging (MPI). MDCT datasets of 44 patients were analyzed to generate bull's eye display of myocardial perfusion and calculate segmental quantitative indices of extent and severity of perfusion defect. Visual interpretation of MDCT-derived bull's eyes was in agreement with rest MPI scores (□=0.79). Quantitative MDCT perfusion data were in good agreement with MPI summed scores: r=0.84; objective detection of perfusion defects using MDCT index resulted in: area under ROC curve=0.87, sensitivity 0.92, specificity 0.91, and accuracy 0.89. Our technique for volumetric analysis of MDCT data allows accurate and objective detection of perfusion defects.
Starting Page	601
Ending Page	604
File Size	353450
Page Count	4
File Format	PDF
ISBN	9781424472819
ISSN	02766547
e-ISBN	9781424472826
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-09-13
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Computers in Cardiology(CinC)
Subject Keyword	Myocardium Computed tomography Visualization Image analysis Testing Nuclear power generation Displays Image segmentation Eyes Data analysis
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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