NDLI: Dynamic non-linear changes in heart rate variability in patients with coronary heart disease and arterial hypertension treated by amlodipine besylate

Content Provider	IEEE Xplore Digital Library
Author	Krstacic, G. Krstacic, A. Martinis, M. Vargovic, E. Knezevic, A. Jembrek-Gostovic, M. Smalcelj, A. Milicic, D. Bergovec, M. Gostovic, M.
Copyright Year	2003
Description	Author affiliation: Inst. for Cardiovascular Disease & Rehabilitation, Zagreb, Croatia (Krstacic, G.)
Abstract	The article emphasizes clinical and prognostic significance of non-linear measures of the heart rate variability (HRV). It was applied on the group of patients with stable coronary heart disease (CHD) and arterial hypertension (AH) before and after 6 months treatment by amlodipine besylate (5 mg daily). Two different methods were applied: Hurst exponent (H) and detrended fluctuation analysis (DFA). Hurst exponent of the R-R series was determined by the range rescaled analysis technique. DFA was used to quantify fractal long-range-correlation properties of heart rate variability. It was found that the short-term fractal scaling exponent (/spl alpha//sub 1/) is significantly lower in patients with CHD, as well as Hurst exponent. But, after 6 months treatment with calcium channel blocker amlodipine besylate the results of HRV are normalize.
Sponsorship	European Soc. of Cardiology Nat. Inst. of Health, USA
Starting Page	485
Ending Page	488
File Size	227753
Page Count	4
File Format	PDF
ISBN	078038170X
ISSN	02766547
DOI	10.1109/CIC.2003.1291198
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2003-09-21
Publisher Place	Greece
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Heart rate variability Cardiac disease Hypertension Electrocardiography Testing Hospitals Fractals Calcium Cardiovascular diseases Medical treatment
Content Type	Text
Resource Type	Article

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