NDLI: Computer controlled induced hypothermia in victims of out-of-hospital cardiac arrest

Content Provider	IEEE Xplore Digital Library
Author	Leor-Librach, R.J. Gmach-Fluk, S. Jasmawie, I. Nachliely, V. Ezra, O.
Copyright Year	2003
Description	Author affiliation: Sanz Med. Center, Laniado Hosp., Netanya, Israel (Leor-Librach, R.J.; Gmach-Fluk, S.; Jasmawie, I.; Nachliely, V.; Ezra, O.)
Abstract	Out-of-hospital cardiac arrest is a condition with high mortality and devastating morbidity. Until most recently there was no specific therapy apart from strict monitoring and supportive care. Results from animal studies and a few recent clinical trials suggest a beneficial effect of induced mild hypothermia on the neurologic outcome. We treated 22 successive patients with 24 hours of induced hypothermia to 34.5/spl deg/C and compared their outcome to our last 16 patients who were hospitalized before we started the project. Patients were connected to a microprocessor-based heat pump that supplied warmed or cooled water to the ThermoWrap/spl trade/ garment worn by the patient. The cooling system we used lowered patients' temperature to a mean of 34.5 /spl plusmn/ 0.7/spl deg/C at a mean time of 6.2 /spl plusmn/ 2.5 hours. 59% of the hypothermia patients were discharged conscious as compared to 25% of the patients who were treated conservatively p<0.03. The mortality rate was 29% in the hypothermia group and 37% in the conservative care group P=NS. We conclude that the computerized cooling system we used, adequately lowered and stabilized our patients' temperature on the desired target level. Induced mild hypothermia is beneficial in victims of out-of-hospital cardiac arrest. The issue of controlled cooling of patients is complex and should be further investigated.
Sponsorship	European Soc. of Cardiology Nat. Inst. of Health, USA
Starting Page	233
Ending Page	234
File Size	115356
Page Count	2
File Format	PDF
ISBN	078038170X
ISSN	02766547
DOI	10.1109/CIC.2003.1291133
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2003-09-21
Publisher Place	Greece
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cardiac arrest Medical treatment Cooling Temperature Patient monitoring Computerized monitoring Animals Clinical trials Heat pumps Water heating
Content Type	Text
Resource Type	Article

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