NDLI: Tachyarrhythmias and electrical instabilities in cardiac tissue

Content Provider	IEEE Xplore Digital Library
Author	Starobin, J.M. Chernyak, Y.B. Cohen, R.J.
Copyright Year	1998
Description	Author affiliation: North Carolina Univ., Greensboro, NC, USA (Starobin, J.M.)
Abstract	Unstable cardiac rhythm is known to precede dangerous cardiac arrhythmias. Despite a considerable body of experimental data the underlying mechanism of electrical instabilities still remains unclear. This study presents a numerical analysis of the dynamic instabilities in the circulation of a pulse in a ring of excitable tissue that helps to determine physical mechanisms of these instabilities and to understand their potential correlation with complex cardiac rhythms. The authors demonstrate that a pulse width begins to oscillate after an initial perturbation for any length of the ring and the corresponding propagation velocity. The oscillations were found to be either damped or incremental. The incremental oscillations occurred when the ratio of the steady-state circulation period to the period of the pulse width oscillations was of the order of /spl sim/0.5. Under the same conditions the external pacing of the ring gives rise to complex rhythms incorporating alternans-like patterns.
Starting Page	365
Ending Page	368
File Size	342503
Page Count	4
File Format	PDF
ISBN	0780352009
ISSN	02766547
DOI	10.1109/CIC.1998.731812
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1998-09-13
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cardiac tissue Rhythm Space vector pulse width modulation Chaos Numerical analysis Steady-state Spirals Bifurcation Character generation Frequency
Content Type	Text
Resource Type	Article

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