NDLI: Population pharmacokinetic/dynamic (PK/PD) modeling via the World Wide Web

Content Provider	IEEE Xplore Digital Library
Author	Botnen, A. Wang, X. Jelliffe, R. Thomas, M. Hoem, N.
Copyright Year	2001
Description	Author affiliation: Sch. of Med., Univ. of Southern California, Los Angeles, CA, USA (Botnen, A.)
Abstract	A new research resource has been developed, allowing organizations with limited facilities for pharmacokinetic/pharmacodynamic (PK/PD) analysis to develop large and nonlinear nonparametric population models. The infrastructure described in this paper is flexible, reliable and secure. These resources are in use today by researchers in a number organizations and countries. Satellite installations continue to grow both nationally and internationally. The computational systems currently being made available through World Wide Web interfaces include the world's eighth largest supercomputer, smaller supercomputers and Beowulf systems. We first give a formulation of the problem. Then we give a description of infrastructure that is being used to overcome the problem. The last section contains an example of how the system is being used today.
Sponsorship	IEEE Comput. Soc. Tech. Committee on Computational Med.
Starting Page	163
Ending Page	168
File Size	362563
Page Count	6
File Format	PDF
ISBN	0769510043
ISSN	10637125
DOI	10.1109/CBMS.2001.941715
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2001-07-26
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Web sites Processor scheduling Web server Computer architecture Logic programming Computer interfaces Database systems Resource management Distributed computing Distributed databases
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging Computer Science Applications

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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