NDLI: Inverse solution of the fetal-circulation model based on ultrasound Doppler measurements

Content Provider	IEEE Xplore Digital Library
Author	Luria, O. Bar, J. Kovo, M. Shalev, J. Barnea, O.
Copyright Year	2012
Description	Author affiliation: Department of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel (Luria, O.; Barnea, O.) \|\| Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon (Bar, J.; Kovo, M.; Shalev, J.)
Abstract	Fetal growth restriction (FGR) is one of the major contributors to adverse perinatal outcome. However, the diagnostic tools currently used for estimating the fetal hemo-dynamic status are still limited. In this study we developed a methodology for estimating fetal hemodynamic parameters. The method is based on a mathematical model of the fetal circulation, an optimization algorithm and measurements of power-Doppler ultrasound. The model estimates parameters of the fetal circulation that are not possible for direct measurement. The method was tested on a cohort of 20 normal and 22 growth-restricted fetuses. In each fetus, power-Doppler velocity waveforms were measured in large number of sites of the fetal circulation. Three-dimensional volume-flow measurements were performed in the placenta to evaluate its resistance to blood flow. Model predictions indicated significant changes in the circulation of FGR fetuses compared to normal fetuses. In the FGR group, the model predicted significant reduction in fetal cardiac output and decreased cardiac output distribution towards the placenta. In FGR fetuses that showed adverse outcome, the model indicated significant increase in cardiac output distribution towards the brain and in the degree of blood shunted by the ductus venosus, indicating severe brain-sparing state in these fetuses. We conclude that patient-specific modeling may be useful in personalizing and optimizing the treatment options in pregnancies complicated by fetal growth-restriction.
Starting Page	1
Ending Page	4
File Size	380730
Page Count	4
File Format	PDF
ISBN	9781467346825
e-ISBN	9781467346818
DOI	10.1109/EEEI.2012.6376962
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-11-14
Publisher Place	Israel
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Doppler effect Mathematical model Hemodynamics Pregnancy Fetus Brain modeling Power Doppler ultrasonography Fetal growth restriction Patient-specific modeling Brain-sparing effect Placental resistance to blood flow
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Examination of the placental circulation by Doppler ultrasound.

Inverse Solution of the Fetal-Circulation Model Based on Ultrasound Doppler Measurements

The application of doppler ultrasound to the study of fetal blood flow in perinatal medicine.

Original contribution what is spared by fetal brain-sparing? fetal circulatory redistribution and behavioral problems in the general population (2008).

Doppler vascular changes in intrauterine growth restriction.

Evaluation of fetal cerebral blood flow perfusion using power Doppler ultrasound angiography (3D-PDA) in growth-restricted fetuses.

Fetal brain sparing in a mouse model of chronic maternal hypoxia

Aortic isthmus and cardiac monitoring of the growth-restricted fetus.

Colour Doppler ultrasound of spiral artery blood flow in the prediction of pre-eclampsia and intrauterine growth restriction.

Inverse solution of the fetal-circulation model based on ultrasound Doppler measurements

Similar Documents

Examination of the placental circulation by Doppler ultrasound.

Inverse Solution of the Fetal-Circulation Model Based on Ultrasound Doppler Measurements

The application of doppler ultrasound to the study of fetal blood flow in perinatal medicine.

Original contribution what is spared by fetal brain-sparing? fetal circulatory redistribution and behavioral problems in the general population (2008).

Doppler vascular changes in intrauterine growth restriction.

Evaluation of fetal cerebral blood flow perfusion using power Doppler ultrasound angiography (3D-PDA) in growth-restricted fetuses.

Fetal brain sparing in a mouse model of chronic maternal hypoxia

Aortic isthmus and cardiac monitoring of the growth-restricted fetus.

Colour Doppler ultrasound of spiral artery blood flow in the prediction of pre-eclampsia and intrauterine growth restriction.

Inverse solution of the fetal-circulation model based on ultrasound Doppler measurements