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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Kui Han Yuan, Y.J. |
| Copyright Year | 2001 |
| Abstract | The LOVE wave devices based on a number of composite structures have been designed and simulated in this paper for use as a bond-rupture biosensor. Bond-rupture biosensors use acoustic energy to probe the bond strength between the sensor substrate and the analyte. The sensitivity and displacement of LOVE wave sensors can be implemented due to energy concentration inside a guiding layer on the surface of a piezoelectric crystal. The choice of substrate and guiding layer material is the critical basic elements in the proper design of a LOVE wave biosensor applications. Finite element method (FEM) is a suitable numerical method to analyze and design the LOVE wave device. A 3-D FEM model has been created and defined to simulate the displacement response of the acoustic wave system. The LOVE wave can be clearly observed, and the total surface displacement can reach a value of 10-11m, which can easily induce the bond rupture between antibody and antigen. A 2-D model has been established to simulate the mass sensitivity with different composite structures of 128° YX LiNbO3, 36° YX LiTaO3, ST-quartz-PMMA and 128° YX LiNbO3, and 36° YX LiTaO3 and ST-quartz-SiO2. These results indicate that the 128° YX LiNbO3PMMA is the most suitable for bond rupture biosensors due to its high sensitivity and maximum displacement on the surface of piezoelectric crystal. |
| Sponsorship | IEEE Sensors Council |
| Starting Page | 2601 |
| Ending Page | 2608 |
| Page Count | 8 |
| File Size | 3391887 |
| File Format | |
| ISSN | 1530437X |
| Volume Number | 14 |
| Issue Number | 8 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2014-01-01 |
| Publisher Place | U.S.A. |
| Access Restriction | One Nation One Subscription (ONOS) |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Load modeling Solid modeling Substrates Biosensors Sensitivity Surface acoustic waves sensitivity Bond rupture finite element method LOVE surface acoustic wave mass loading |
| Content Type | Text |
| Resource Type | Article |
| Subject | Instrumentation Electrical and Electronic Engineering |
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