NDLI: Microparticle Concentration and Separation by Traveling-Wave Dielectrophoresis (twDEP) for Digital Microfluidics

Content Provider	IEEE Xplore Digital Library
Author	Yuejun Zhao Ui-Chong Yi Sung Kwon Cho
Copyright Year	1992
Abstract	This paper describes highly efficient in-droplet particle concentration and separation where particles are concentrated and separated into droplets by traveling-wave dielectrophoresis (DEP) and subsequent electrowetting-on-dielectric droplet splitting. A successful concentration for 5-mum aldehyde sulfate (AS) latex particles was experimentally achieved using microfabricated devices, showing that 98% of the total particles were concentrated into a split daughter droplet. In addition, in-droplet particle separation was successfully achieved using the following two different cases of particle mixtures: case 1) a mixture of 5-mum AS latex beads and 8-mum glass beads; and case 2) a mixture of ground pine (GP) spores and 8-mum glass beads. In case 1), 97% of the total AS beads were separated into one split droplet and 77% of the total glass beads into the other split droplet. In case 2), over 92% of the GP spores were separated into a split daughter droplet, whereas 86% of the glass beads were separated into the other split daughter droplet. In all these concentration and separation experiments, the applied frequency and the conductivity medium are key parameters influencing the concentration and separation performance, which have been optimally determined by measuring the DEP and electrorotation spectra of the used particles prior to the concentration and separation experiments. This integrated in-droplet separation and concentration method may provide an additional functionality to digital microfluidics.
Sponsorship	IEEE Electron Devices Society American Society of Mechanical Engineering (ASME)
Starting Page	1472
Ending Page	1481
Page Count	10
File Size	1124129
File Format	PDF
ISSN	10577157
Volume Number	16
Issue Number	6
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-12-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Dielectrophoresis Microfluidics Microchannel Glass Fungi Frequency Electrokinetics Electrodes Conductivity measurement Dielectric measurements traveling wave dielectrophoresis (twDEP) Digital microfluidics electrowetting on dielectric (EWOD) lab-on-a-chip
Content Type	Text
Resource Type	Article
Subject	Mechanical Engineering Electrical and Electronic Engineering

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