NDLI: Sampling considerations for high resolution small animal SPECT

Content Provider	IEEE Xplore Digital Library
Author	Damiani, C. Cesca, N. Di Domenico, G. Moretti, E. Sabba, N. Uccelli, L. Zavattini, G. Del Guerra, A.
Copyright Year	1963
Abstract	Using the small animal hybrid PET/SPECT scanner YAP-(S)PET we demonstrate how we can improve both image quality and spatial resolution in SPECT modality, by acquiring data with sampling steps smaller than the detector intrinsic sampling pitch. Due to the planar configuration of our pixellated detector we can easily perform this by shifting detector heads from the central position of an arbitrarily small step tangential to the field of view. This acquisition technique, together with the knowledge of the detector response function, allows us to determine the best sampling step as a trade-off between image quality, resolution, and acquisition time. In the real case, the more one samples the FOV with a finer step, the more one reduces aliasing (better image quality). Furthermore one also records higher frequency components in the image spectrum (better spatial resolution). To demonstrate how this technique can enhance the image, images of capillaries and phantoms will be presented. In particular the trend of resolution versus sampling step is reported. In this paper we present two different kinds of results: first we reconstruct images, acquired with different sampling modalities, with the same spatial frequency cut-off; in this way we show how the decreasing of the sampling step enhances image quality for a fixed resolution. Second we reconstruct images by recovering all possible spatial frequencies so as to enhance spatial resolution. All images are deconvolved for the frequency response (transfer function) of our system by implementing deconvolution in a standard filtered back projection (FBP) algorithm. The results show that it is possible to approach the 2 mm resolution limit imposed by the crystal; in fact we can recover resolution down to 2.2 mm (/spl plusmn/3.5%).
Sponsorship	IEEE Nuclear and Plasma Sciences Society Computer Applications in Nuclear and Plasma Sciences (CANPS) Lawrence Berkeley Lab. Lawrence Livermore Nat. Lab. APS College of William and Mary Continuous Electron Beam Accelerator Facility NASA Defence Nuclear Agency Sandia National Laboratories Jet Propulsion Laboratory Brookhaven Nat. Lab. Lawrence Livermore Nat. Lab IEEE/NPPS Radiat. Effects Committee Defence Nuclear Agency/DoD Sandia National Laboratories/DOE Jet Propulsion Laboratory/NASA Phillips Lab./DoD
Starting Page	555
Ending Page	559
Page Count	5
File Size	344571
File Format	PDF
ISSN	00189499
Volume Number	52
Issue Number	3
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2005-06-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Sampling methods Animals Spatial resolution Image sampling Image quality Detectors Image resolution Frequency Image reconstruction Positron emission tomography spatial resolution Fourier transforms sampling theory single photon emission computed tomography (SPECT)
Content Type	Text
Resource Type	Article
Subject	Nuclear and High Energy Physics Electrical and Electronic Engineering Nuclear Energy and Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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