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Detection of chromosomal inversions using non-repetitive nucleic acid probes
| Content Provider | NASA Technical Reports Server (NTRS) |
|---|---|
| Copyright Year | 2014 |
| Description | A method and a kit for the identification of chromosomal inversions are described. Single-stranded sister chromatids are generated, for example by CO-FISH. A plurality of non-repetitive, labeled probes of relatively small size are hybridized to portions of only one of a pair of single-stranded sister chromatids. If no inversion exists, all of the probes will hybridize to a first chromatid. If an inversion has occurred, these marker probes will be detected on the sister chromatid at the same location as the inversion on the first chromatid. |
| File Size | 831253 |
| Page Count | 8 |
| File Format | |
| Alternate Webpage(s) | http://archive.org/details/NASA_NTRS_Archive_20150003185 |
| Archival Resource Key | ark:/13960/t9q28x85p |
| Language | English |
| Publisher Date | 2014-01-14 |
| Access Restriction | Open |
| Subject Keyword | Aerospace Medicine Patents Inversions Fluorescence Marking Nucleic Acids Deoxyribonucleic Acid Cytogenesis Genetic Engineering Chemical Detection Chromosomes Chromosome Aberrations Paints Kits Ntrs Nasa Technical Reports Server (ntrs) Nasa Technical Reports Server Aerodynamics Aircraft Aerospace Engineering Aerospace Aeronautic Space Science |
| Content Type | Text |
| Resource Type | Patent |
