NDLI: Contribution of MMP14-expressing cancer-associated fibroblasts in the tumor immune microenvironment to progression of colorectal cancer

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Day +60 WT1 assessment on CD34 selected bone marrow better predicts relapse and mortality after allogeneic stem cell transplantation in acute myeloid leukemia patients

Characterization of genetic predisposition to molecular subtypes of breast cancer in Brazilian patients

Relationship of dose to vascular target volumes and local failure in pancreatic cancer patients undergoing neoadjuvant chemoradiation

Expression and prognosis analysis of PAQR5 in kidney cancer

Comprehensive analysis of TP53 and SPOP mutations and their impact on survival in metastatic prostate cancer

High serum IL-17A is associated with bone destruction in newly diagnosed multiple myeloma patients

Tumor vessel co-option: The past & the future

A comparative study of functional MRI in predicting response of regional nodes to induction chemotherapy in patients with nasopharyngeal carcinoma

Efficacy and safety of taxanes combined with chemotherapy drugs in advanced triple negative breast cancer: A meta-analysis of 26 randomized controlled trials

Incidence of pelvic high-grade serous carcinoma after isolated STIC diagnosis: A systematic review of the literature

ErbB4 in the brain: Focus on high grade glioma

Dynamic monitoring revealed a slightly prolonged waiting time for total gastrectomy during the COVID-19 pandemic without increasing the short-term complications

An overview of agents and treatments for PDGFRA-mutated gastrointestinal stromal tumors

Identification and validation of the role of c-Myc in head and neck squamous cell carcinoma

Applying artificial intelligence technology to assist with breast cancer diagnosis and prognosis prediction

The safety of neoadjuvant chemotherapy combined with non-tube nofasting fast-track surgery for esophageal carcinoma

Combined proton radiography and irradiation for high-precision preclinical studies in small animals

Efficacy, safety and predictors of combined fruquintinib with programmed death-1 inhibitors for advanced microsatellite-stable colorectal cancer: A retrospective study

Adjuvant chemotherapy may improve long-term outcomes in stage IB non-small cell lung cancer patients with previous malignancies: A propensity score-matched analysis

Editorial: Women in surgical oncology: 2021

Current perspectives on clinical use of exosomes as novel biomarkers for cancer diagnosis

Publication trends and hotspots of drug resistance in colorectal cancer during 2002-2021: A bibliometric and visualized analysis

Busulfan and thiotepa as a conditioning regimen for autologous stem cell transplantation in patients with multiple myeloma: A study of the Korean Multiple Myeloma Working Party (KMMWP-1801 study)

Endocytosis of the thrombopoietin receptor Mpl regulates megakaryocyte and erythroid maturation in mice

MRI radiomics predicts progression-free survival in prostate cancer

Chondroitin sulfate proteoglycan 4 expression in chondrosarcoma: A potential target for antibody-based immunotherapy

Differentiation of different stages of brain tumor infiltration using optical coherence tomography: Comparison of two systems and histology

Intratumor heterogeneity of driver mutations and TMB distribution in 30 early-stage LUAD patients with multiple lesions

Corrigendum: The NFAT3/RERG complex in luminal breast cancers is required to inhibit cell invasion and may be correlated with an absence of axillary lymph nodes colonization

Neoadjuvant tislelizumab and tegafur/gimeracil/octeracil (S-1) plus oxaliplatin in patients with locally advanced gastric or gastroesophageal junction cancer: Early results of a phase 2, single-arm trial

Solitary extramedullary plasmacytoma in the lung misdiagnosed as lung cancer: A case report and literature review

A personalized DVH prediction model for HDR brachytherapy in cervical cancer treatment

Development and validation of a prognosis prediction model based on 18 endoplasmic reticulum stress-related genes for patients with lung adenocarcinoma

DNA damage response and repair genes in advanced bone and soft tissue sarcomas: An 8-gene signature as a candidate predictive biomarker of response to trabectedin and olaparib combination

Predictive value of NLR and PLR in response to preoperative chemotherapy and prognosis in locally advanced gastric cancer

Stage-dependent prognostic shift in mismatch repair-deficient tumors: Assessing patient outcomes in stage II and III colon cancer

Micronodular thymoma with lymphoid stroma: Contrast-enhanced CT features with histopathological correlation in 10 patients

Case Report: A rare case of primary hepatic Castleman’s disease mimicking a liver tumor

Impact of local anesthetics on epigenetics in cancer

Ultrasound-guided microwave ablation in the treatment of early-stage tongue cancer

Auto-segmentation for total marrow irradiation

m6A-related lncRNAs are potential biomarkers for the prognosis of COAD patients

Primary hepatopancreatobiliary lymphoma: Pathogenesis, diagnosis, and management

Tumor-infiltrating immune cells based TMEscore and related gene signature is associated with the survival of CRC patients and response to fluoropyrimidine-based chemotherapy

Dissecting a hypoxia-related angiogenic gene signature for predicting prognosis and immune status in hepatocellular carcinoma

Prediction of response to systemic treatment by kinetics of circulating tumor DNA in metastatic pancreatic cancer

La protein regulates protein expression by binding with the mRNAs of target genes and participates the pathological process of ovarian cancer

Identification of cuprotosis-mediated subtypes, the development of a prognosis model, and influence immune microenvironment in hepatocellular carcinoma

Case report: Changes in serum bevacizumab concentration in a hemodialysis patient with unresectable colorectal cancer treated with FOLFIRI plus bevacizumab

Systematic assessment of microRNAs associated with lung cancer and physical exercise

A preoperative model based on gadobenate-enhanced MRI for predicting microvascular invasion in hepatocellular carcinomas (≤ 5 cm)

Combined treatment of marizomib and cisplatin modulates cervical cancer growth and invasion and enhances antitumor potential in vitro and in vivo

SHMT2 regulates serine metabolism to promote the progression and immunosuppression of papillary renal cell carcinoma

An emerging prognosis prediction model for multiple myeloma: Hypoxia-immune related microenvironmental gene signature

Patient selection, inter-fraction plan robustness and reduction of toxicity risk with deep inspiration breath hold in intensity-modulated radiotherapy of locally advanced non-small cell lung cancer

Case report: Significant liver atrophy due to giant cystic pheochromocytoma

Pseudo-progression with osimertinib after definitive chemoradiation in unresectable epidermal growth factor receptor mutation positive of stage III non-small cell lung cancer: A case report

Photobiomodulation therapy in management of cancer therapy-induced side effects: WALT position paper 2022

Role of mitochondrial translation in remodeling of energy metabolism in ER/PR(+) breast cancer

Lurbinectedin in small cell lung cancer

Early [18]FDG PET/CT scan predicts tumor response in head and neck squamous cell cancer patients treated with erlotinib adjusted per smoking status

Adjuvant crizotinib in high-risk uveal melanoma following definitive therapy

Role of echogenic foci in ultrasonographic risk stratification of thyroid nodules: Echogenic focus scoring in the American College of Radiology Thyroid Imaging Reporting and Data System

Mass spectrometric analysis of TRPM6 and TRPM7 from small intestine of omeprazole-induced hypomagnesemic rats

Comprehensive analysis of tissue proteomics in patients with papillary thyroid microcarcinoma uncovers the underlying mechanism of lymph node metastasis and its significant sex disparities

Integration of healthy volunteers in early phase clinical trials with immuno-oncological compounds

Radiation induces ESCRT pathway dependent CD44v3+ extracellular vesicle production stimulating pro-tumor fibroblast activity in breast cancer

Cost-effectiveness analysis of personalised versus standard dosimetry for selective internal radiation therapy with TheraSphere in patients with hepatocellular carcinoma

Case report: New subtype of gastric adenocarcinoma arising from an H. pylori infection-negative stomach: Foveolar epithelium and mucous neck cell-mixed type adenocarcinoma

Reprogramming lipid metabolism as potential strategy for hematological malignancy therapy

MTBP enhances the activation of transcription factor ETS-1 and promotes the proliferation of hepatocellular carcinoma cells

Is robotic distal pancreatectomy better than laparoscopic distal pancreatectomy after the learning curve? A systematic review and meta-analysis

CRISPR-based knockout screening identifies the loss of MIEF2 to enhance oxaliplatin resistance in colorectal cancer through inhibiting the mitochondrial apoptosis pathway

Endoscopic transorbital extradural anterior clinoidectomy: A stepwise surgical technique and case series study [SevEN-013]

In-vivo thermodynamic exploration of gas-based intraperitoneal hyperthermia

Case report: Intravitreal methotrexate in intraocular acute lymphoblastic leukemia

Robust treatment planning in scanned carbon-ion radiotherapy for pancreatic cancer: Clinical verification using in-room computed tomography images

Tumor acidity: From hallmark of cancer to target of treatment

Influence of the external breast prosthesis on the postural control of women who underwent mastectomy: Cross-sectional study

Molecular subtypes, clinical significance, and tumor immune landscape of angiogenesis-related genes in ovarian cancer

Bioactive peptides from venoms against glioma progression

Editorial: Mechanisms of resistance to the targeted therapy and immunotherapy in cutaneous melanoma

Effect of glycated hemoglobin A1c on the survival of patients with oral squamous cell carcinoma: A multi-institutional database cohort study

Scalable radiotherapy data curation infrastructure for deep-learning based autosegmentation of organs-at-risk: A case study in head and neck cancer

Atypical presentation of patients with chronic myeloid leukemia in chronic phase—Case report

LncRNA GAS5 represses stemness and malignancy of gliomas via elevating the SPACA6-miR-125a/let-7e Axis

Improving the clinical workflow of a MR-Linac by dosimetric evaluation of synthetic CT

Leveraging teachable moments in cancer prevention by improving HPV vaccination in health professional students (HPS): A systematic review

GCLDNet: Gastric cancer lesion detection network combining level feature aggregation and attention feature fusion

DCE-MRI radiomics models predicting the expression of radioresistant-related factors of LRP-1 and survivin in locally advanced rectal cancer

Enhancing anti-tumour innate immunity by targeting the DNA damage response and pattern recognition receptors in combination with radiotherapy

A novel cuproptosis-related lncRNA nomogram to improve the prognosis prediction of gastric cancer

Emerging PD-1/PD-L1 targeting immunotherapy in non-small cell lung cancer: Current status and future perspective in Japan, US, EU, and China

Acidic urine is associated with poor prognosis in patients with bladder cancer undergoing radical cystectomy

Eligibility, uptake and response to germline genetic testing in women with DCIS

Integrated analysis of the M2 macrophage-related signature associated with prognosis in ovarian cancer

Efficacy and safety of sintilimab plus XELOX as a neoadjuvant regimen in patients with locally advanced gastric cancer: A single-arm, open-label, phase II trial

Ultrasound radiomics model-based nomogram for predicting the risk Stratification of gastrointestinal stromal tumors

Endoscopic transorbital approach to the cavernous sinus: Cadaveric anatomy study and clinical application (‡SevEN-009)

Socioeconomic deprivation and survival outcomes in primary central nervous system lymphomas

Pediatric glioblastoma cells are sensitive to drugs that inhibit eIF2α dephosphorylation and its phosphomimetic S51D variant

3-Dimensional mesothelioma spheroids provide closer to natural pathophysiological tumor microenvironment for drug response studies

MRI-guided focal or integrated boost high dose rate brachytherapy for recurrent prostate cancer

Different functional lung-sparing strategies and radiotherapy techniques for patients with esophageal cancer

Bile is a reliable and valuable source to study cfDNA in biliary tract cancers

Establishing a prognostic model of ferroptosis- and immune-related signatures in kidney cancer: A study based on TCGA and ICGC databases

MAC-spinal meningioma score: A proposal for a quick-to-use scoring sheet of the MIB-1 index in sporadic spinal meningiomas

Body composition change during neoadjuvant chemotherapy for breast cancer

The 18F-PSMA-1007 PET/CT performance on metastasis status and therapy assessment in oligo-metastasis prostate cancer

Socioeconomic status-based survival disparities and nomogram prediction for patients with multiple myeloma: Results from American and Chinese populations

A happy cell stays home: When metabolic stress creates epigenetic advantages in the tumor microenvironment

Cost-Effectiveness of Pembrolizumab for the treatment of Non–Small-Cell lung cancer: A systematic review

GREM1 is a novel serum diagnostic marker and potential therapeutic target for pancreatic ductal adenocarcinoma

Characteristics and survival in bone metastatic breast cancer patients with different hormone receptor status: A population-based cohort study

Autophagy in gastrointestinal cancers

DNA methylation regulators-related molecular patterns and tumor immune landscape in hepatocellular carcinoma

Preoperative supplementation of calcitriol and calcium relieves symptom and extent of hypocalcemia in patients undergoing total thyroidectomy and bilateral central compartment neck dissection: A prospective, randomized, open-label, parallel-controlled clinical study

Patient-reported outcomes for patients with breast cancer undergoing radiotherapy: A single-center registry experience

Active surveillance of highly suspicious thyroid nodules cohort in China shows a worse psychological status in younger patients

Clinical outcomes of robotic-assisted laparoscopic partial nephrectomy with renal hypothermia perfusion by renal artery balloon catheter in treating patients with complex renal tumors

Machine learning prediction of prostate cancer from transrectal ultrasound video clips

Exosomal MiR-4261 mediates calcium overload in RBCs by downregulating the expression of ATP2B4 in multiple myeloma

Recurrent paraganglioma of the vulva: A rare case report and review of the literature

Potential 18F-RGD PET/CT and DCE-MRI Imaging-Based Biomarkers for Postoperative Survival Prediction Among Patients With Newly Diagnosed Glioblastoma Treated With Bevacizumab and Chemoradiotherapy

Microwave ablation plus camrelizumab monotherapy or combination therapy in non-small cell lung cancer

Ultrasound-based radiomics XGBoost model to assess the risk of central cervical lymph node metastasis in patients with papillary thyroid carcinoma: Individual application of SHAP

Adjuvant chemotherapy is not a decisive factor in improving the overall survival of pulmonary sarcoma: A population-based study

Current Status and Prospects of Research on Ischemia-Reperfusion Injury and Ferroptosis

Rare pulmonary embolism in a pregnant patient: A primary diffused pulmonary artery myxofibrosarcoma case report

A more effective CT synthesizer using transformers for cone-beam CT-guided adaptive radiotherapy

Full-course resection control strategy in glioma surgery using both intraoperative ultrasound and intraoperative MRI

Exploring the origin of the cancer stem cell niche and its role in anti-angiogenic treatment for glioblastoma

The impact of depression on survival of head and neck cancer patients: A population-based cohort study

Cervical cancer screening in high-altitude areas in China: A large cross-section study of 25,173 women in northern Tibet

Parotid metastases from primary lung cancer: Case series and systematic review of the features

An integrated somatic and germline approach to aid interpretation of germline variants of uncertain significance in cancer susceptibility genes

Design, synthesis, and anticancer activity of three novel palbociclib derivatives

Corrigendum: Blockade of uttroside B-induced autophagic pro-survival signals augments its chemotherapeutic efficacy against hepatocellular carcinoma

Neutrophils: Musketeers against immunotherapy

Based on clinical Ki-67 expression and serum infiltrating lymphocytes related nomogram for predicting the diagnosis of glioma-grading

Circular RNAs regulate parental gene expression: A new direction for molecular oncology research

Misdiagnosed appendiceal mucinous neoplasms and primary ovarian mucinous tumors present with different pre- and intraoperative characteristics

The hedgehog pathway in hematopoiesis and hematological malignancy

Fanconi anemia and dyskeratosis congenita/telomere biology disorders: Two inherited bone marrow failure syndromes with genomic instability

Advances in endoscopic resection techniques of small gastric tumors originating from the muscularis propria

Comparison of surgical resection and radiofrequency ablation for stages I and II elderly hepatocellular carcinoma patients (≥ 65 years): A SEER population-based propensity score matching’s study

Intraoperative low-dose dopamine is associated with worse survival in patients with hepatocellular carcinoma: A propensity score matching analysis

P2X7 receptor isoform B is a key drug resistance mediator for neuroblastoma

Global research trends of artificial intelligence applied in esophageal carcinoma: A bibliometric analysis (2000-2022) via CiteSpace and VOSviewer

Substrate stiffness effect on molecular crosstalk of epithelial-mesenchymal transition mediators of human glioblastoma cells

Drosophila as a toolkit to tackle cancer and its metabolism

The Sinai Robotic Surgery Trial in HPV-related oropharyngeal squamous cell carcinoma (SIRS 2.0 trial) – study protocol for a phase II non-randomized non-inferiority trial

Suppressor of fused associates with dissemination patterns in patients with glioma

The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis

CDK4/6 inhibitors versus PI3K/AKT/mTOR inhibitors in women with hormone receptor-positive, HER2-negative metastatic breast cancer: An updated systematic review and network meta-analysis of 28 randomized controlled trials

Editorial: Emerging engineering approaches in cancer immunotherapy

Serum cytokine levels for predicting immune-related adverse events and the clinical response in lung cancer treated with immunotherapy

Sirolimus combined with interferon-alpha 2b therapy for giant hepatic epithelioid hemangioendothelioma: a case report

The history of small extracellular vesicles and their implication in cancer drug resistance

Case report: Candidiasis of gastrojejunostomosis after pancreaticoduodenectomy: Preliminary experience from two cases

Bile-derived exosome noncoding RNAs as potential diagnostic and prognostic biomarkers for cholangiocarcinoma

Phase II INTERACT-ION study: ezabenlimab (BI 754091) and mDCF (docetaxel, cisplatin, and 5-fluorouracil) followed by chemoradiotherapy in patients with Stage III squamous cell anal carcinoma

Cell origin and genome profile difference of penoscrotum invasive extramammary Paget disease compared with its in situ counterpart

Clinical applications of circulating tumor cells in hepatocellular carcinoma

Corrigendum: Progression-free survival and time to progression as potential surrogate endpoints for overall survival in chemoradiotherapy trials in limited-stage small-cell lung cancer: A systematic review and meta-analysis

Characterization of ex vivo and in vivo intraoperative neurosurgical confocal laser endomicroscopy imaging

Risk and prognosis of secondary bladder cancer after radiation therapy for pelvic cancer

Case Report: Resolution of radiation pneumonitis with androgens and growth hormone

Comprehensive analysis to identify a novel PTEN-associated ceRNA regulatory network as a prognostic biomarker for lung adenocarcinoma

RPP40 is a prognostic biomarker and correlated with tumor microenvironment in uterine corpus endometrial carcinoma

Targeting the key cholesterol biosynthesis enzyme squalene monooxygenasefor cancer therapy

POD1UM-303/InterAACT 2: A phase III, global, randomized, double-blind study of retifanlimab or placebo plus carboplatin–paclitaxel in patients with locally advanced or metastatic squamous cell anal carcinoma

Pulmonary mucoepidermoid carcinoma in the Chinese population: A clinical characteristic and prognostic analysis

Precision oncology for RET-related tumors

Effect of pulsed field ablation on solid tumor cells and microenvironment

Case report: Ultrasound-guided intrauterine biopsy and RF ablation therapy for fetal posterior neck solid tumor: first successful report

The value of combined PET/MRI, CT and clinical metabolic parameters in differentiating lung adenocarcinoma from squamous cell carcinoma

Surgery and chemotherapy cannot improve the survival of patients with early-stage mucosa-associated lymphoid tissue derived primary pulmonary lymphoma

Alterations in the gastric microbiota and metabolites in gastric cancer: An update review

Evaluation of circulating tumor DNA as a prognostic biomarker for metastatic pancreatic adenocarcinoma

The effects of glucocorticoids and immunosuppressants on cancer outcomes in checkpoint inhibitor therapy

Survival benefit of thermal ablation therapy for patients with stage II-III non-small cell lung cancer: A propensity-matched analysis

Contrast-enhanced ultrasound of granular cell tumor in breast: A case report with review of the literature

The prognostic potential of fragmented CK18 serum levels in HCC patients reflecting disease progression and overall hepatocyte damage

Is ICI-based therapy better than chemotherapy for metastatic NSCLC patients who develop EGFR-TKI resistance? A real-world investigation

Microwave ablation therapy assisted by artificial pneumothorax and artificial hydrothorax for lung cancer adjacent to the vital organs

COVID-19 vaccination in advanced skin cancer patients receiving systemic anticancer treatment: A prospective singlecenter study investigating seroconversion rates

FN1 is a prognostic biomarker and correlated with immune infiltrates in gastric cancers

Clinical relevance of the combined analysis of circulating tumor cells and anti-tumor T-cell immunity in metastatic breast cancer patients

Recent Perspectives on the Mechanism of Recurrence After Ablation of Hepatocellular Carcinoma: A Mini-Review

Molecular subtyping of CD5+ diffuse large B-cell lymphoma based on DNA-targeted sequencing and Lymph2Cx

Colon cancer patient with long-term colon stent placement: Case report and literature review

Periodontal disease and cancer risk: A nationwide population-based cohort study

Selection of the surgical approach for patients with cStage IA lung squamous cell carcinoma: A population-based propensity score matching analysis

Clinical impact of inferior mesenteric vein preservation during left hemicolectomy with low ligation of the inferior mesenteric artery for distal transverse and descending colon cancers: A comparative study based on computed tomography

Effects of Wee1 inhibitor adavosertib on patient-derived high-grade serous ovarian cancer cells are multiple and independent of homologous recombination status

LncRNA-ENST00000543604 exerts a tumor-promoting effect via miRNA 564/AEG-1 or ZNF326/EMT and predicts the prognosis of and chemotherapeutic effect in colorectal cancer

Application of a combined radiomics nomogram based on CE-CT in the preoperative prediction of thymomas risk categorization

Phase separation in epigenetics and cancer stem cells

PKIB involved in the metastasis and survival of osteosarcoma

The role of the bone microenvironment in regulating myeloma residual disease and treatment

Corrigendum: ASPM is a prognostic biomarker and correlates with immune infiltration in kidney renal clear cell carcinoma and liver hepatocellular carcinoma

Multimodality imaging in lobular breast cancer: Differences in mammography, ultrasound, and MRI in the assessment of local tumor extent and correlation with molecular characteristics

FOXM1 is regulated by DEPDC1 to facilitate development and metastasis of oral squamous cell carcinoma

Comprehensive analysis of m6A circRNAs identified in colorectal cancer by MeRIP sequencing

Tracking fibrosis in myeloproliferative neoplasms by CCR2 expression on CD34+ cells

Commentary: High-metastatic melanoma cells promote the metastatic capability of low-metastatic melanoma cells via exosomal transfer of miR-411-5p

Local ablation of pulmonary malignancies abutting pleura: Evaluation of midterm local efficacy and safety

Corrigendum: Polymeric immunoglobulin receptor suppresses colorectal cancer through the AKT-FOXO3/4 axis by downregulating LAMB3 expression

Development and validation of a novel fibroblast scoring model for lung adenocarcinoma

A cuproptosis and copper metabolism–related gene prognostic index for head and neck squamous cell carcinoma

Emerging roles of ferroptosis in glioma

Clinical independent prognostic factors and overall survival prognostic nomogram for intracranial subependymoma: A SEER population-based analysis 2004–2016

Prediction of survival in oropharyngeal squamous cell carcinoma using machine learning algorithms: A study based on the surveillance, epidemiology, and end results database

Racial disparities in liver cancer: Evidence for a role of environmental contaminants and the epigenome

A predictive model for early death in elderly patients with gastric cancer: A population-based study

Comprehensive germline and somatic genomic profiles of Chinese patients with biliary tract cancer

Deep learning models for predicting the survival of patients with chondrosarcoma based on a surveillance, epidemiology, and end results analysis

Prognostic role of the platelet to lymphocyte ratio (PLR) in the clinical outcomes of patients with advanced lung cancer receiving immunotherapy: A systematic review and meta-analysis

Effect of infection with hepatitis B virus on the survival outcome of diffuse large B-cell lymphoma in the prophylactic antiviral era

Progress in gallbladder cancer with lymph node metastasis

Importance of the endometrial immune environment in endometrial cancer and associated therapies

Rectosigmoid sparing en bloc pelvic resection for fixed ovarian tumors: Surgical technique and perioperative and oncologic outcomes

Expression, correlation, and prognostic significance of different nicotinic acetylcholine receptors, programed death ligand 1, and dopamine receptor D2 in lung adenocarcinoma

Incidence and risk factors of suicide among patients with pancreatic cancer: A population-based analysis from 2000 to 2018

Monocytes acquire prostate cancer specific chromatin conformations upon indirect co-culture with prostate cancer cells

Predicting recurrence and metastasis risk of endometrial carcinoma via prognostic signatures identified from multi-omics data

Respiratory system toxicity induced by immune checkpoint inhibitors: A real-world study based on the FDA adverse event reporting system database

Exploring pathological signatures for predicting the recurrence of early-stage hepatocellular carcinoma based on deep learning

LncRNA-AC009948.5 promotes invasion and metastasis of lung adenocarcinoma by binding to miR-186-5p

Rapid response to monotherapy with MEK inhibitor trametinib for a lung adenocarcinoma patient harboring primary SDN1-BRAF fusion: A case report and literature review

Safety and immunogenicity of the COVID-19 vaccine BNT162b2 for patients with breast and gynecological cancer on active anticancer therapy: Results of a prospective observational study

The Texas collaborative center for hepatocellular cancer: Reducing liver cancer mortality in Texas through coordination, collaboration and advocacy

Predicting the molecular subtypes of breast cancer using nomograms based on three-dimensional ultrasonography characteristics

Associations of MDM2 rs2279744 and TP53 rs1042522 polymorphisms with cervical cancer risk: A meta-analysis and systematic review

Anxiety and depression risk in Taiwan women with breast cancer and cervical cancer

The effect of race/ethnicity on cancer-specific mortality after salvage radical prostatectomy

IL-8 and its role as a potential biomarker of resistance to anti-angiogenic agents and immune checkpoint inhibitors in metastatic renal cell carcinoma

Incidence, clinical characteristics, and prognostic nomograms for patients with myeloid sarcoma: A SEER-based study

What predicts the clinical benefits of PARP inhibitors in platinum-sensitive recurrent ovarian cancer: A real-world single-center retrospective cohort study from China

Efficacy, safety, and feasibility of volumetric modulated arc therapy for synchronous bilateral breast cancer management

Prediction and clinical impact of delayed lymphopenia after chemoradiotherapy in locally advanced non-small cell lung cancer

Role of PSMA PET-guided metastases-directed therapy in oligometastatic recurrent prostate cancer

miR-31-3p functions as a tumor suppressor by directly targeting GABBR2 in prostate cancer

Selinexor inhibits growth of patient derived chordomas in vivo as a single agent and in combination with abemaciclib through diverse mechanisms

Using combined CT-clinical radiomics models to identify epidermal growth factor receptor mutation subtypes in lung adenocarcinoma

Integrated driver mutations profile of chinese gastrointestinal-natural killer/T-cell lymphoma

Circulating cell-free DNA and IL-10 from cerebrospinal fluids aid primary vitreoretinal lymphoma diagnosis

Research progress on RNA−binding proteins in breast cancer

Degradation strategy of cyclin D1 in cancer cells and the potential clinical application

Deep learning-based low-dose CT for adaptive radiotherapy of abdominal and pelvic tumors

A narrative review of circulating tumor cells clusters: A key morphology of cancer cells in circulation promote hematogenous metastasis

Recommendations for the prevention, screening, diagnosis, staging, and management of cervical cancer in areas with limited resources: Report from the International Gynecological Cancer Society consensus meeting

Development and validation of a novel prognostic model for patients with surgically resected esophageal squamous cell carcinoma

Comparative review of pharmacological therapies in individuals with HER2-positive advanced breast cancer with focus on hormone receptor subgroups

Decellularization of xenografted tumors provides cell-specific in vitro 3D environment

In vitro elucidation of antioxidant, antiproliferative, and apoptotic potential of yeast-derived β-1,3-glucan particles against cervical cancer cells

Case report: Rapid recurrence of a chronic subdural haematoma associated with prostate cancer metastasis to a haematoma capsule

Inter-fraction heart displacement during voluntary deep inspiration breath hold radiation therapy without visual feedback measured by daily CBCT

Hypoxic stress and hypoxia-inducible factors in leukemias

Machine learning model for the prediction of prostate cancer in patients with low prostate-specific antigen levels: A multicenter retrospective analysis

The low affinity A2B adenosine receptor enhances migratory and invasive capacity in vitro and angiogenesis in vivo of glioblastoma stem-like cells

The diagnostic value of a nomogram based on multimodal ultrasonography for thyroid-nodule differentiation: A multicenter study

Development and validation of cuproptosis-associated prognostic signatures in WHO 2/3 glioma

Pro-tumorigenic role of type 2 diabetes-induced cellular senescence in colorectal cancer

Radiomics feature as a preoperative predictive of lymphovascular invasion in early-stage endometrial cancer: A multicenter study

Establishing a novel model of malignant airway stenosis in rabbit

The evolving role of morphology in endometrial cancer diagnostics: From histopathology and molecular testing towards integrative data analysis by deep learning

Characterization of coagulation-related gene signature to predict prognosis and tumor immune microenvironment in skin cutaneous melanoma

MM-UNet: A multimodality brain tumor segmentation network in MRI images

Three categories of similarities between the placenta and cancer that can aid cancer treatment: Cells, the microenvironment, and metabolites

High expression of nectin-1 indicates a poor prognosis and promotes metastasis in hepatocellular carcinoma

Anatomical liver resection improves surgical outcomes for combined hepatocellular-cholangiocarcinoma: A propensity score matched study

Study protocol for a prospective, open-label, single-arm, phase II study on the combination of tislelizumab, nab-paclitaxel, gemcitabine, and concurrent radiotherapy as the induction therapy for patients with locally advanced and borderline resectable pancreatic cancer

Publication trends of research on conjunctival melanoma during 1997–2022: A 25-year bibliometric study

Intravesical recurrence factors and outcome after radical nephroureterectomy for upper tract urothelial carcinoma: Multivariate analysis with propensity score matching

Mechanical and metabolic interplay in the brain metastatic microenvironment

COVID-19 in cancer patients with diabetes in Pakistan: Clinical features and management

Treatment outcomes of 156 patients with cervical esophageal cancers treated with definitive radiation therapy- A single-institution experience of a rare cancer

Distinct sociodemographic differences in incidence and survival rates for human papillomavirus (HPV)-like, non-HPV-like, and “other”-like oral cavity and pharynx cancers: An analysis of Surveillance, Epidemiology and End Results (SEER) Program data

Congenital midline spinal hamartoma in an infant with DICER1 syndrome: A case report

Drug-induced tumor-specific cytotoxicity in a whole tissue ex vivo model of human pancreatic ductal adenocarcinoma

Circ0038632 modulates MiR-186/DNMT3A axis to promote proliferation and metastasis in osteosarcoma

Aberrant DNA methylation in multiple myeloma: A major obstacle or an opportunity?

The top 100 most cited papers on endometrial carcinoma: A bibliometric analysis

Efficacy and safety of immune checkpoint inhibitors-combined antiangiogenic drugs in the treatment of hepatocellular carcinoma: A systematic review and meta analysis

Evaluation of D-TACE combined with endovascular brachytherapy for HCC with MPVTT

Case Report: Prolonged clinical benefit with sequential trastuzumab-containing treatments in a patient with advanced extramammary Paget disease of the groin

A novel glycosyltransferase-related lncRNA signature correlates with lung adenocarcinoma prognosis

Colchicine as a novel drug for the treatment of osteosarcoma through drug repositioning based on an FDA drug library

Advancements in the treatment of metastatic hormone-sensitive prostate cancer

Current perspectives on recurrent HPV-mediated oropharyngeal cancer

Relationship between metabolic reprogramming and drug resistance in breast cancer

Sodium oligomannate combined with rivastigmine may improve cerebral blood flow and cognitive impairment following CAR-T cell therapy: A case report

Machine learning for lymph node metastasis prediction of in patients with gastric cancer: A systematic review and meta-analysis

Evaluation of aliphatic acid metabolism in bladder cancer with the goal of guiding therapeutic treatment

Role of 18FDG PET/CT metabolic parameters in predicting hematological toxicity during chemoradiotherapy for locally advanced cervical cancer

Targeting O-GlcNAcylation to overcome resistance to anti-cancer therapies

lncRNA pair as candidate diagnostic signature for colorectal cancer based on the within-sample relative expression levels

Navigating preemptive and therapeutic donor lymphocyte infusions in advanced myeloid malignancies by high-sensitivity chimerism analysis

Stellera chamaejasme L. extracts in the treatment of glioblastoma cell lines: Biological verification based on a network pharmacology approach

Genomic and microbial factors affect the prognosis of anti-pd-1 immunotherapy in nasopharyngeal carcinoma

Efficacy and safety of anlotinib plus programmed death-1 blockade versus anlotinib monotherapy as second or further-line treatment in advanced esophageal squamous cell carcinoma: A retrospective study

Metabolic management of microenvironment acidity in glioblastoma

Epigenetic regulation of cutaneous T-cell lymphoma is mediated by dysregulated lncRNA MALAT1 through modulation of tumor microenvironment

Comparison of clinical outcomes between cone beam CT-guided thermal ablation and helical tomotherapy in pulmonary metastases from hepatocellular carcinoma

A meta-analysis of clinicopathologic features that predict necrosis or fibrosis at post-chemotherapy retroperitoneal lymph node dissection in individuals receiving treatment for non-seminoma germ cell tumours

Corrigendum: Ubiquitin C-Terminal hydrolase L5 (UCHL5) accelerates the growth of endometrial cancer via activating the Wnt/β-catenin signaling pathway

BTN3A3 inhibits the proliferation, migration and invasion of ovarian cancer cells by regulating ERK1/2 phosphorylation

Treatment, pathological characteristics, and prognosis of pulmonary inflammatory myofibroblastic tumor–a retrospective study of 8 cases

Case report: B7-H3 CAR-T therapy partially controls tumor growth in a basal cell carcinoma patient

Evolutions in the management of non-small cell lung cancer: A bibliometric study from the 100 most impactful articles in the field

Robot-assisted esophagectomy may improve perioperative outcome in patients with esophageal cancer – a single-center experience

The role of radiomics with machine learning in the prediction of muscle-invasive bladder cancer: A mini review

Ultrasound radiomics in personalized breast management: Current status and future prospects

Non-coding RNA in cancer drug resistance: Underlying mechanisms and clinical applications

Post-chemotherapy pneumonia in Chinese patients with diffuse large B-cell lymphoma: Outcomes and predictive model

Machine learning-featured Secretogranin V is a circulating diagnostic biomarker for pancreatic adenocarcinomas associated with adipopenia

Primary intrathoracic liposarcomas: A clinicopathologic and molecular study of 43 cases in one of the largest medical centers of China

Evaluation of the Stellae-123 prognostic gene expression signature in acute myeloid leukemia

Incidence of bifid pancreatic duct in pancreaticoduodenectomy and its impact on clinically relevant postoperative pancreatic fistula

Ginseng-derived nanoparticles inhibit lung cancer cell epithelial mesenchymal transition by repressing pentose phosphate pathway activity

Angiogenesis in NENs, with a focus on gastroenteropancreatic NENs: from biology to current and future therapeutic implications

ACO1 and IREB2 downregulation confer poor prognosis and correlate with autophagy-related ferroptosis and immune infiltration in KIRC

Immune checkpoint inhibitors for PD-1/PD-L1 axis in combination with other immunotherapies and targeted therapies for non-small cell lung cancer

Expression and clinical value of circRNAs in serum extracellular vesicles for gastric cancer

Blood neurofilament light chain as a biomarker for monitoring and predicting paclitaxel-induced peripheral neuropathy in patients with gynecological cancers

A combined microinvasive trans-submandibular and nasendoscopy surgical approach to dissect recurrent or radiotherapy-insensitive nasopharyngeal carcinoma

Downregulation of ZNF280A inhibits proliferation and tumorigenicity of colorectal cancer cells by promoting the ubiquitination and degradation of RPS14

Safety and efficacy of indocyanine green near-infrared fluorescent imaging-guided lymph nodes dissection during radical gastrectomy for gastric cancer: A systematic review and meta-analysis

Case Report: A case of uterine leiomyosarcoma metastasized to the vena cava, excised with the aid of preoperative CT three-dimensional imaging

Therapeutic potential of NR4A1 in cancer: Focus on metabolism

Combinatorial delivery of CPI444 and vatalanib loaded on PEGylated graphene oxide as an effective nanoformulation to target glioblastoma multiforme: In vitro evaluation

Corrigendum: Post-operative complications and nipple necrosis rates between conventional and robotic nipple-sparing mastectomy

Minimal residual disease detection by next-generation sequencing in multiple myeloma: Promise and challenges for response-adapted therapy

Prognostication in palliative radiotherapy—ProPaRT: Accuracy of prognostic scores

A computational method for large-scale identification of esophageal cancer-related genes

The prognostic value of immune-related genes AZGP1, SLCO5A1, and CTF1 in Uveal melanoma

The function and regulatory mechanism of RNA-binding proteins in breast cancer and their future clinical treatment prospects

Lentiviral vector–based xenograft tumors as candidate reference materials for detection of HER2-low breast cancer

Malignancy risk of gastrointestinal stromal tumors evaluated with noninvasive radiomics: A multi-center study

The immune-related role of beta-2-microglobulin in melanoma

Preoperative Naples prognostic score is a reliable prognostic indicator for newly diagnosed glioblastoma patients

Adhesion strength and anti-tumor agents regulate vinculin of breast cancer cells

Expression and clinical significance of Cathepsin K and MMPs in invasive non-functioning pituitary adenomas

The potential of soluble programmed death-ligand 1 (sPD-L1) as a diagnosis marker for colorectal cancer

Whole transcriptome sequencing reveals a TCF4-ZNF384 fusion in acute lymphoblastic leukemia

Analysis of prognosis and treatment decisions for patients with second primary lung cancer following esophageal cancer

Immune checkpoint inhibitor-related pneumonitis in non-small cell lung cancer: A review

Successful conversion surgery for locally advanced gallbladder cancer after gemcitabine and nab-paclitaxel chemotherapy

Erythropoietin receptor regulates tumor mitochondrial biogenesis through iNOS and pAKT

Applications of diffusion tensor imaging integrated with neuronavigation to prevent visual damage during tumor resection in the optic radiation area

Clinical utility of a 1.5 T magnetic resonance imaging-guided linear accelerator during conventionally fractionated and hypofractionated prostate cancer radiotherapy

Autophagy-related prognostic signature characterizes tumor microenvironment and predicts response to ferroptosis in gastric cancer

Prognostic value of pretreatment serum albumin−globulin ratio in urothelial carcinoma: A systematic review and meta-analysis

Case report: The effective response to pembrolizumab in combination with bevacizumab in the treatment of a recurrent glioblastoma with multiple extracranial metastases

ASNS can predict the poor prognosis of clear cell renal cell carcinoma

Contribution of MMP14-expressing cancer-associated fibroblasts in the tumor immune microenvironment to progression of colorectal cancer

Editorial: Long-non coding RNAs in renal cell carcinoma

Multi-center verification of the influence of data ratio of training sets on test results of an AI system for detecting early gastric cancer based on the YOLO-v4 algorithm

Heterotypic neutrophil-in-tumor structure: A novel pathological feature first discovered in the tissues of OPSCC

Prognostic value of normal sodium levels in patients with metastatic renal cell carcinoma receiving tyrosine kinase inhibitors

One-year recovery from breast cancer: Importance of tumor and treatment-related factors, resilience, and sociodemographic factors for health-related quality of life

LRP-1-dependent control of calpain expression and activity: A new mechanism regulating thyroid carcinoma cell adhesion

CASC11 and PVT1 spliced transcripts play an oncogenic role in colorectal carcinogenesis

Clinical analysis of 13 cases of primary squamous-cell thyroid carcinoma

Identification of PLAUR-related ceRNA and immune prognostic signature for kidney renal clear cell carcinoma

Editorial: Surgical interventions in gastric cancer

Adjuvant chemotherapy can benefit the survival of stage I lung adenocarcinoma patients with tumour spread through air spaces after resection: Propensity-score matched analysis

Normofractionated and moderately hypofractionated proton therapy: comparison of acute toxicity and early quality of life outcomes

Effectiveness of PARP inhibition in enhancing the radiosensitivity of 3D spheroids of head and neck squamous cell carcinoma

Computed tomography-based radiomics quantification predicts epidermal growth factor receptor mutation status and efficacy of first-line targeted therapy in lung adenocarcinoma

The molecular mechanisms of ferroptosis and its role in glioma progression and treatment

Neoadjuvant Savolitinib targeted therapy stage IIIA-N2 primary lung adenocarcinoma harboring MET Exon 14 skipping mutation: A case report

Intersections of endocrine pathways and the epithelial mesenchymal transition in endometrial cancer

Efficacy of immune checkpoint inhibitors in non-small cell lung cancer: A systematic review and meta-analysis

Editorial: Rising stars in neuro-oncology and neurosurgical oncology 2021

Trends in incidence and mortality of esophageal cancer in China 1990−2019: A joinpoint and age-period-cohort analysis

Case Report: Adaptive radiotherapy in the radiation salvage of prostate cancer

Axillary management for early invasive breast cancer patients: Who will truly benefit?

Anoikis resistance in diffuse glioma: The potential therapeutic targets in the future

Comparison Between First Line Target Therapy and Immunotherapy in Different Prognostic Categories of BRAF Mutant Metastatic Melanoma Patients: An Italian Melanoma Intergroup Study

The nomogram for the prediction of overall survival in patients with metastatic lung adenocarcinoma undergoing primary site surgery: A retrospective population-based study

131I-Caerin 1.1 and 131I-Caerin 1.9 for the treatment of non-small-cell lung cancer

Anemia tolerance versus blood transfusion on long-term outcomes after colorectal cancer surgery: A retrospective propensity-score-matched analysis

Case report: A rare case of pulmonary mucormycosis caused by Lichtheimia ramosa in pediatric acute lymphoblastic leukemia and review of Lichtheimia infections in leukemia

Targeting TRAF3IP2 inhibits angiogenesis in glioblastoma

Dose rate and dose robustness for proton transmission FLASH-RT treatment in lung cancer

Application of artificial intelligence in the diagnosis of subepithelial lesions using endoscopic ultrasonography: a systematic review and meta-analysis

A predictive nomogram for lymph node metastasis in part-solid invasive lung adenocarcinoma: A complement to the IASLC novel grading system

Case report: Fetal cervical immature teratoma and copy number variations

Fate decisions of breast cancer stem cells in cancer progression

Primary Ewing’s sarcoma of sphenoid sinus: A case report and literature review

Development of an ultrasound-based radiomics nomogram to preoperatively predict Ki-67 expression level in patients with breast cancer

Extensive patient-to-patient single nucleus transcriptome heterogeneity in pheochromocytomas and paragangliomas

Fatty acid desaturase 1 (FADS1) is a cancer marker for patient survival and a potential novel target for precision cancer treatment

Corrigendum: Single-cell technologies to decipher the immune microenvironment in myeloid neoplasms: Perspectives and opportunities

CalliSpheres® microsphere transarterial chemoembolization combined with 125I brachytherapy for patients with non–small‐cell lung cancer liver metastases

The bacteria inside human cancer cells: Mainly as cancer promoters

Subcutaneous soft tissue metastases from esophageal squamous cell carcinoma with neuroendocrine differentiation: Case report and literature review

Image quality and whole-lesion histogram and texture analysis of diffusion-weighted imaging of breast MRI based on advanced ZOOMit and simultaneous multislice readout-segmented echo-planar imaging

Development and validation of cuproptosis-related gene signature in the prognostic prediction of liver cancer

Gene expression analysis reveals a 5-gene signature for progression-free survival in prostate cancer

The global research status and trends of the application of endoscopic ultrasonography in pancreatic tumors over the last decades: A bibliometric study

Continuous subcortical language mapping in awake glioma surgery

Corrigendum: Cucurbitacin B, purified and characterized from the rhizome of Corallocarpus epigaeus exhibits anti-melanoma potential

Development and external validation of a dynamic nomogram to predict the survival for adenosquamous carcinoma of the pancreas

Nivolumab drug holiday in patients treated for metastatic renal cell carcinoma: A real-world, single-centre experience

An immediate postoperative response to therapy assessment can help avoid unnecessary RAI therapy

Estimation risk of lymph nodal invasion in patients with early-stage cervical cancer: Cervical cancer application

Primary versus secondary antiemetic prophylaxis with NK1 receptor antagonists in patients affected by gastrointestinal malignancies and treated with a doublet or triplet combination regimen including oxaliplatin and/or irinotecan plus fluoropyrimidines: A propensity score matched analysis

Choosing the optimal immunotherapeutic strategies for non-small cell lung cancer based on clinical factors

Matricellular protein tenascin C: Implications in glioma progression, gliomagenesis, and treatment

Eosinophil as a biomarker for diagnosis, prediction, and prognosis evaluation of severe checkpoint inhibitor pneumonitis

Bone metastases in newly diagnosed patients with thyroid cancer: A large population-based cohort study

An automated approach for predicting glioma grade and survival of LGG patients using CNN and radiomics

HMOX1 promotes lung adenocarcinoma metastasis by affecting macrophages and mitochondrion complexes

Molecular determinants of outcomes in meningiomas

Case report: Giant unilocular prostate cystadenoma: A rarer condition with a single cystic mass

Advances in prognostic and therapeutic targets for hepatocellular carcinoma and intrahepatic cholangiocarcinoma: The hippo signaling pathway

Fucosylated exosomal miRNAs as promising biomarkers for the diagnosis of early lung adenocarcinoma

Small but strong: Pivotal roles and potential applications of snoRNAs in hematopoietic malignancies

Osteoporosis, fracture and survival: Application of machine learning in breast cancer prediction models

Patient-derived cancer models: Valuable platforms for anticancer drug testing

Immune microenvironment characteristics in multiple myeloma progression from transcriptome profiling

Combined SUVmax and localized colonic wall thickening parameters to identify high-risk lesions from incidental focal colorectal 18F-FDG uptake foci

Identification of the novel prognostic biomarker, MLLT11, reveals its relationship with immune checkpoint markers in glioma

Evaluation and multi-institutional validation of a novel urine biomarker lncRNA546 to improve the diagnostic specificity of prostate cancer in PSA gray-zone

Risk of secondary malignant neoplasms in children following proton therapy vs. photon therapy for primary CNS tumors: A systematic review and meta-analysis

The crosstalk effect between ferrous and other ions metabolism in ferroptosis for therapy of cancer

Comparing the blood oxygen level–dependent fluctuation power of benign and malignant musculoskeletal tumors using functional magnetic resonance imaging

Effective dissecting range and prognostic significance of lateral pelvic lymph node dissection for middle-low rectal cancer patients with lateral pelvic lymph node metastasis: Results of a large multicenter lateral node collaborative group in China

Cyclin-dependent kinase inhibitors in malignant hematopoiesis

Investigational cyclin-dependent kinase 4/6 inhibitor GLR2007 demonstrates activity against isocitrate dehydrogenase wild-type glioblastoma and other solid tumors in mice xenograft models

The survival benefit of different lymph node yields in radical prostatectomy for pN1M0 prostate cancer patients: Implications from a population-based study

Compound Kushen injection reduces severity of radiation-induced gastrointestinal mucositis in rats

A commentary on 125I seed brachytherapy for refractory loco-regional recurrence of non-anaplastic thyroid cancer

Development and validation of a deep learning model for breast lesion segmentation and characterization in multiparametric MRI

Survival, treatment pattern, and treatment outcome in patients with cervical cancer metastatic to distant lymph nodes

Clinical course and management of insidious adrenal crisis manifested initially as hyperpyrexia secondary to pembrolizumab: Case reports and literature review

Integrated molecular and pharmacological characterization of patient-derived xenografts from bladder and ureteral cancers identifies new potential therapies

A new technique for performing interstitial implants for gynecologic malignancies using transvaginal ultrasound guidance

Automated segmentation of colorectal liver metastasis and liver ablation on contrast-enhanced CT images

Personalized treatment of extensive stage small cell lung cancer: A case report and literature review

Sex-related disparities in outcomes of cholangiocarcinoma patients in treatment trials

Current treatments for non-small cell lung cancer

Global research trend of esophageal squamous cell carcinoma from 2012 to 2022: a bibliometric analysis

Clinical study of total bone marrow combined with total lymphatic irradiation pretreatment based on tomotherapy in hematopoietic stem cell transplantation of acute leukemia

Deep learning-based automatic segmentation for size and volumetric measurement of breast cancer on magnetic resonance imaging

Diagnostic value of contrast-enhanced ultrasound in intravenous leiomyomatosis: a single-center experiences

Heterogeneity of resistant mechanisms in an EGFR-TKI relapsed patient with EGFR amplification and response to nimotuzumab: A case report

Screening of co-pathogenic genes of non-alcoholic fatty liver disease and hepatocellular carcinoma

The role of B cells in cancer development

Microwave ablation with local pleural anesthesia for subpleural pulmonary nodules: our experience

Application of artificial intelligence in glioma researches: A bibliometric analysis

Comprehensive analysis of ferroptosis-related gene signatures as a potential therapeutic target for acute myeloid leukemia: A bioinformatics analysis and experimental verification

Design and experimental validation of OPERA_MET-A panel for deep methylation analysis by next generation sequencing

A radiomics nomogram for invasiveness prediction in lung adenocarcinoma manifesting as part-solid nodules with solid components smaller than 6 mm

Frontiers of ferroptosis research: An analysis from the top 100 most influential articles in the field

Identification of methylation signatures associated with CAR T cell in B-cell acute lymphoblastic leukemia and non-hodgkin’s lymphoma

Global adoption of single-shot targeted intraoperative radiotherapy (TARGIT-IORT) for breast cancer—better for patients, better for healthcare systems

Induction chemotherapy with paclitaxel, carboplatin and cetuximab for locoregionally advanced nasopharyngeal carcinoma: A single-center, retrospective study

A review of granulocyte colony-stimulating factor receptor signaling and regulation with implications for cancer

Is liquid biopsy the future commutator of decision-making in liver transplantation for hepatocellular carcinoma?

GlioMarker: An integrated database for knowledge exploration of diagnostic biomarkers in gliomas

Case report: Salvage capmatinib therapy in KIF5B-MET fusion-positive lung adenocarcinoma with resistance to telisotuzumab vedotin

Real-time fully automated dosimetric computation for CT images in the clinical workflow: A feasibility study

Polymorphisms in ERCC4 and ERCC5 and risk of cancers: Systematic research synopsis, meta-analysis, and epidemiological evidence

Non-coding RNA in rhabdomyosarcoma progression and metastasis

The role of fascin-1 in the pathogenesis, diagnosis and management of respiratory related cancers

A systematic review of margin status in retroperitoneal liposarcomas: Does the R0 margin matter?

Integrative transcriptional characterization of cell cycle checkpoint genes promotes clinical management and precision medicine in bladder carcinoma

Prognostic significance of CNSL at diagnosis of childhood B-cell acute lymphoblastic leukemia: A report from the South China Children’s Leukemia Group

Methionine cycle-dependent regulation of T cells in cancer immunity

Comprehensive analysis: Necroptosis-related lncRNAs can effectively predict the prognosis of glioma patients

Molecular and pathological subtypes related to prostate cancer disparities and disease outcomes in African American and European American patients

Dosimetric Evaluation of Commercially Available Flat vs. Self-Produced 3D-Conformal Silicone Boluses for the Head and Neck Region

Comparison of Efficacy and Safety Between Immunotherapy and Docetaxel Monotherapy in NSCLC Patients

Salvia chinensis Benth Inhibits Triple-Negative Breast Cancer Progression by Inducing the DNA Damage Pathway

Editorial: Global excellence in oncology: Asia and Australia 2021

Identification of genes from ten oncogenic pathways associated with mortality and disease progression in glioblastoma

Long-term outcomes of prostate intensity-modulated radiation therapy incorporating a simultaneous intra-prostatic MRI-directed boost

The modulation of ion channels in cancer chemo-resistance

The prognostic influence of histological subtypes of micropapillary tumors on patients with lung adenocarcinoma ≤ 2 cm

Efficacy and safety of pembrolizumab on cervical cancer: A systematic review and single-arm meta-analysis

Long non-coding RNA LINC00152 in cancer: Roles, mechanisms, and chemotherapy and radiotherapy resistance

CCL5 mediates breast cancer metastasis and prognosis through CCR5/Treg cells

Nomogram individually predicts the risk for distant metastasis and prognosis value in female differentiated thyroid cancer patients: A SEER-based study

Papillary thyroid microcarcinoma with contralateral large humerus metastasis and cervical lymph node metastasis: A case report

Editorial: Liquid biopsy: A tool for better understanding of the metastatic process ecosystem

Construction of a solid Cox model for AML patients based on multiomics bioinformatic analysis

Folate-modified erythrocyte membrane nanoparticles loaded with Fe3O4 and artemisinin enhance ferroptosis of tumors by low-intensity focused ultrasound

PDPN marks a subset of aggressive and radiation-resistant glioblastoma cells

Unearthing novel fusions as therapeutic targets in solid tumors using targeted RNA sequencing

Influence of sex on survival rates of HPV-positive oropharyngeal cancers

Comparison of real-world data (RWD) analysis on efficacy and post-progression outcomes with pembrolizumab plus chemo vs chemo alone in metastatic non-squamous non-small cell lung cancer with PD-L1 < 50%

OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway

Comprehensive Analysis of the Prognostic Value and Immune Infiltration of Butyrophilin Subfamily 2/3 (BTN2/3) Members in Pan-Glioma

Case report: Identification of a novel heterozygous germline ERCC2 mutation in a patient with dermatofibrosarcoma protuberans

Radiation Oncology: Future Vision for Quality Assurance and Data Management in Clinical Trials and Translational Science

Hemangioblastoma in the lateral ventricle: An extremely rare case report

Survival after wedge resection versus lobectomy for stage IA second primary NSCLC with previous lung cancer-directed surgery

SpyGlass-Guided Photodynamic Therapy for Unresectable Cholangiocarcinoma: A Case Report and Review of the Literature

Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer

The role of RHAMM in cancer: Exposing novel therapeutic vulnerabilities

A novel signature based on necroptosis-related long non-coding RNAs for predicting prognosis of patients with glioma

Prognostic value of the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in laryngeal cancer: What should we expect from a meta-analysis?

Development and validation of a deep learning model to predict survival of patients with esophageal cancer

Positive surgical margins may not affect the survival of patients with renal cell carcinoma after partial nephrectomy: A meta-analysis based on 39 studies

Mechanistic insights into the clinical Y96D mutation with acquired resistance to AMG510 in the KRASG12C

Doxorubicin-induced cardiotoxicity is mediated by neutrophils through release of neutrophil elastase

Relapsed and refractory yolk sac tumor of the peritoneum (mesentery): A case report and literature review

Is periodontal disease a risk indicator for urogenital cancer? A systematic review and meta-analysis of cohort studies

Exploring the pharmacological mechanism of compound kushen injection in the treatment of breast cancer using in vitro experiments: Coupling network pharmacology with GEO database

Editorial: Advancements in immunology and immunotherapy for breast cancer

Mesenchymal stem cells derived from adipose tissue accelerate the progression of colon cancer by inducing a MTCAF phenotype via ICAM1/STAT3/AKT axis

BI 2536 induces gasdermin E-dependent pyroptosis in ovarian cancer

Case Report: Dacomitinib is effective in lung adenocarcinoma with rare EGFR mutation L747P and brain metastases

Adenosquamous Carcinoma of Skene’s Gland: A Case Report and Literature Review

Identifying cancer tissue-of-origin by a novel machine learning method based on expression quantitative trait loci

Adverse outcomes of artificial pneumothorax under right bronchial occlusion for patients with thoracoscopic-assisted oesophagectomy in the prone position versus the semiprone position

Machine-learning-based contrast-enhanced computed tomography radiomic analysis for categorization of ovarian tumors

Chemotherapy-associated oral microbiome changes in breast cancer patients

Growth hormone associated with treatment efficacy of immune checkpoint inhibitors in gastric cancer patients

Fluorescein-guided surgery for the resection of pilocytic astrocytomas: A multicentric retrospective study

Anti-PD-1 sintilimab-induced bilateral optic neuropathy in non-small cell lung cancer: A case report and literature review

Association between microRNA 671 polymorphisms and the susceptibility to soft tissue sarcomas in a Chinese population

Radiomics based on pretreatment MRI for predicting distant metastasis of nasopharyngeal carcinoma: A preliminary study

Quality assessment of clinical practice guidelines on psychological distress of cancer patients using the AGREE II instrument

Review of Radiomics- and Dosiomics-based Predicting Models for Rectal Cancer

Comprehensive analysis of androgen receptor status in prostate cancer with neuroendocrine differentiation

Successful treatment with docetaxel plus nintedanib in a patient with lung adenocarcinoma and pulmonary fibrosis: A case report and literature review

Maintenance therapy for AML after allogeneic HCT

Long-term oncological outcomes of oncoplastic breast-conserving surgery after a 10-year follow-up – a single center experience and systematic literature review

The global change of gene expression pattern caused by PTEN mutation affects the prognosis of glioblastoma

Pretreatment blood biomarkers combined with magnetic resonance imaging predict responses to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

The prognostic significance of inflammation-immunity-nutrition score on postoperative survival and recurrence in hepatocellular carcinoma patients

Nutritional support during the hospital stay is cost-effective for preventing adverse outcomes in patients with cancer

Small extracellular vesicle DNA-mediated horizontal gene transfer as a driving force for tumor evolution: Facts and riddles

Editorial: Virtual surgical planning and 3d printing in head and neck tumor resection and reconstruction

Molecular classification grade 3 endometrial endometrioid carcinoma using a next-generation sequencing–based gene panel

Cuproptosis predicts the risk and clinical outcomes of lung adenocarcinoma

The quantum leap in therapeutics for advanced ALK+ non-small cell lung cancer and pursuit to cure with precision medicine

Precision Breast Cancer Medicine: Early Stage Triple Negative Breast Cancer—A Review of Molecular Characterisation, Therapeutic Targets and Future Trends

Revealing the intratumoral heterogeneity of non-DS acute megakaryoblastic leukemia in single-cell resolution

Current understanding of the human microbiome in glioma

Review: Precise sarcoma patient-derived orthotopic xenograft (PDOX) mouse models enable identification of novel effective combination therapies with the cyclin-dependent kinase inhibitor palbociclib: A strategy for clinical application

Survival outcomes analysis according to mismatch repair status in locally advanced rectal cancer patients treated with neoadjuvant chemoradiotherapy

Mapping phenotypic heterogeneity in melanoma onto the epithelial-hybrid-mesenchymal axis

Double heterozygous pathogenic variants prevalence in a cohort of patients with hereditary breast cancer

Swin transformer-based GAN for multi-modal medical image translation

Differential prognostic impact of stratified additional chromosome abnormalities on disease progression among Malaysian chronic myeloid leukemia patients undergoing treatment with imatinib mesylate

Integrated analysis of anti-tumor roles of BAP1 in osteosarcoma

Editorial: Molecular influences in therapies in ovarian cancer

Comparison of perioperative outcomes with or without routine chest tube drainage after video-assisted thoracoscopic pulmonary resection: A systematic review and meta-analysis

Prediction of BRAF mutation status in glioblastoma multiforme by preoperative ring enhancement appearances on MRI

Comparison of hook-wire and medical glue for CT-guided preoperative localization of pulmonary nodules

The role of hypoxia-inducible factor-1 alpha in multidrug-resistant breast cancer

Predicting chemotherapy response in non-small-cell lung cancer via computed tomography radiomic features: Peritumoral, intratumoral, or combined?

Volumetric modulated arc therapy versus tomotherapy for late T-stage nasopharyngeal carcinoma

Case Report: Efficacy of ensartinib treatment in pulmonary inflammatory myofibroblastic tumor with a rare GCC2-ALK fusion

Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis

Chemotherapy reinforces anti-tumor immune response and enhances clinical efficacy of immune checkpoint inhibitors

New insights into the prognosis of intraocular malignancy: Interventions for association mechanisms between cancer and diabetes

Presence of the GFI1-36N single nucleotide polymorphism enhances the response of MLL-AF9 leukemic cells to CDK4/6 inhibition

Proton therapy in the treatment of hepatocellular carcinoma

Hepatoid adenocarcinoma of the duodenal papilla with hepatic metastases: A case report and literature review

Case report: Major pathologic response induced by neoadjuvant treatment using BRAF and MEK inhibitors in a patient with stage IIIA lung adenocarcinoma harboring BRAF V600E-mutation

18F-FDG PET/CT-based radiomics nomogram for the preoperative prediction of lymph node metastasis in gastric cancer

SkinNet-16: A deep learning approach to identify benign and malignant skin lesions

Expression profiles of m6A RNA methylation regulators, PD-L1 and immune infiltrates in gastric cancer

Circulating inflammatory cells in patients with metastatic breast cancer: Implications for treatment

Inhibitory of active dual cancer targeting 5-Fluorouracil nanoparticles on liver cancer in vitro and in vivo

Comparison of various surgical incisions in parotidectomy: A systematic review and network meta-analysis

Proton pump inhibitors and sensitization of cancer cells to radiation therapy

Feasibility and clinical applicability of genomic profiling based on cervical smear samples in patients with endometrial cancer

The clinical impact of endoscopic ultrasound-guided fine-needle aspiration on the patients with low-risk pancreatic cystic lesions

Polo-like kinase-1, Aurora kinase A and WEE1 kinase are promising druggable targets in CML cells displaying BCR::ABL1-independent resistance to tyrosine kinase inhibitors

HAMP as a Prognostic Biomarker for Colorectal Cancer Based on Tumor Microenvironment Analysis

The Patient’s Perspective on Proton Radiotherapy of Skull Base Meningioma: A Retrospective Cross-Sectional Survey

Proton induced DNA double strand breaks at the Bragg peak: Evidence of enhanced LET effect

The potential effects and mechanisms of breast inflammatory lesions on the occurrence and development of breast cancer

Epithelial–myoepithelial carcinoma of the nasopharynx: A case report and review of the literature

Prognostic value of 12 m7G methylation-related miRNA markers and their correlation with immune infiltration in breast cancer

Novel myeloma patient-derived xenograft models unveil the potency of anlotinib to overcome bortezomib resistance

Role of intraoperative patients positioning in endoscopic full-thickness resection of large gastric tumors under general anesthesia

Case report and literature review: thyroid carcinoma showing intrathyroid thymic carcinoma

Correlation of dynamic contrast-enhanced MRI and diffusion-weighted MR imaging with prognostic factors and subtypes of breast cancers

First case report of spontaneous biliary pleural fistula diagnosed using near infrared region I/II fluorescence of indocyanine green

Development of 3-dimensional printed simulation surgical training models for endoscopic endonasal and transorbital surgery

Azacitidine and donor lymphocyte infusion for patients with relapsed acute myeloid leukemia and myelodysplastic syndromes after allogeneic hematopoietic stem cell transplantation: A meta-analysis

Polymeric immunoglobulin receptor suppresses colorectal cancer through the AKT-FOXO3/4 axis by downregulating LAMB3 expression

Application of deep learning in the real-time diagnosis of gastric lesion based on magnifying optical enhancement videos

Efficacy and safety of indocyanine green tracer-guided lymph node dissection in minimally invasive radical gastrectomy for gastric cancer: A systematic review and meta-analysis

Estradiol mediates the interaction of LINC01541 and miR-429 to promote angiogenesis of G1/G2 endometrioid adenocarcinoma in-vitro: A pilot study

Allogeneic Hematopoietic Stem Cell Transplantation for Mixed or Overlap Myelodysplastic/Myeloproliferative Disorders

Different multiparametric MRI-based radiomics models for differentiating stage IA endometrial cancer from benign endometrial lesions: A multicenter study

PD-1 and LAG-3 expression in EBV-associated pediatric Hodgkin lymphoma has influence on survival

Computer-aided diagnosis of cervical dysplasia using colposcopic images

Conditional cause-specific survival after chemotherapy and local treatment for primary stage IV breast cancer: A population-based study

PD-L1 expression, tumor mutational burden, and immune cell infiltration in non-small cell lung cancer patients with epithelial growth factor receptor mutations

Safety, tolerability, and pharmacokinetics/pharmacodynamics of JMT103 in patients with bone metastases from solid tumors

Clinical comparative study of glasses-free 3D and 2D thoracoscopic surgery in minimally invasive esophagectomy

Efficacy and safety profile of COVID-19 mRNA vaccine in patients with hematological malignancies: Systematic review and meta-analysis

Construction and experimental verification of user-friendly molecular subtypes mediated by immune-associated genes in hepatocellular carcinoma

Upregulation of XIAP promotes lung adenocarcinoma brain metastasis by modulating ceRNA network

Editorial: Molecular mechanisms in breast cancer progression and metastasis

Small molecule MMRi62 targets MDM4 for degradation and induces leukemic cell apoptosis regardless of p53 status

MAFG-AS1 is a prognostic biomarker and facilitates prostate cancer progression

Editorial: Multi-target directed ligands for the treatment of cancer

Glucose transporters: Important regulators of endometrial cancer therapy sensitivity

Combination of 18F-FDG PET/CT and convex probe endobronchial ultrasound elastography for intrathoracic malignant and benign lymph nodes prediction

Case Report: A rare case of small bowel obstruction secondary to plasma cell myeloma

Assessing the robustness of radiomics/deep learning approach in the identification of efficacy of anti–PD-1 treatment in advanced or metastatic non-small cell lung carcinoma patients

Comparison of 3DCRT and IMRT out-of-field doses in pediatric patients using Monte Carlo simulations with treatment planning system calculations and measurements

A nomogram to predict survival probability of gastric cancer patients undergoing radical surgery and adjuvant chemotherapy

Genetic variants in autophagy-related gene ATG2B predict the prognosis of colorectal cancer patients receiving chemotherapy

Beneficial effects of preoperative superselective embolization on carotid body tumor surgery: A 13-year single-center experience

Percutaneous ultrasound-guided core needle biopsy for the diagnosis of cardiac tumors: Optimizing the treatment strategy for patients with intermural and pericardial cardiac tumors

Visual analysis of global research output of lymphedema based on bibliometrics

Iron accumulation typifies renal cell carcinoma tumorigenesis but abates with pathological progression, sarcomatoid dedifferentiation, and metastasis

Design and Fabrication of a Liver-on-a-chip Reconstructing Tissue-tissue Interfaces

Tumor-specific T cell-mediated upregulation of PD-L1 in myelodysplastic syndrome cells does not affect T-cell killing

Influences on cognitive outcomes in adult patients with gliomas: A systematic review

Baduanjin’s impact on quality of life and sleep quality in breast cancer survivors receiving aromatase inhibitor therapy: a randomized controlled trial

Diagnostic accuracy of Raman spectroscopy in oral squamous cell carcinoma

Epidemiological characteristics and risk factors of lung adenocarcinoma: A retrospective observational study from North China

Neoadjuvant chemoradiotherapy for resectable gastric cancer: A meta-analysis

Long-term treatment outcome of Castleman’s disease: A real-world experience

Clinical and molecular evaluation of patients with ovarian cancer in the context of drug resistance to chemotherapy

Case report: Mesothelioma and BAP1 tumor predisposition syndrome: Implications for public health

Prognostic significance of copy number variation in B-cell acute lymphoblastic leukemia

Robotic-assisted thoracic surgery following neoadjuvant chemoimmunotherapy in patients with stage III non-small cell lung cancer: A real-world prospective cohort study

The emerging potentials of lncRNA DRAIC in human cancers

Anticancer effect of Indanone-based thiazolyl hydrazone derivative on p53 mutant colorectal cancer cell lines: An in vitro and in vivo study

Corrigendum: The risk of heart disease-related death among anaplastic astrocytoma patients after chemotherapy: A SEER population-based analysis

Comprehensive analysis of the endoplasmic reticulum stress-related long non-coding RNA in bladder cancer

An exploratory study on the checkout rate of circulating tumor cells and the prediction of efficacy of neoadjuvant therapy and prognosis in patients with HER-2-positive early breast cancer

Mitochondria dysfunction in circulating tumor cells

Clinical application of parathyroid autotransplantation in endoscopic radical resection of thyroid carcinoma

Potential utility of miRNAs for liquid biopsy in breast cancer

Discovery of spirooxindole-derived small-molecule compounds as novel HDAC/MDM2 dual inhibitors and investigation of their anticancer activity

Reparative properties of human glioblastoma cells after single exposure to a wide range of X-ray doses

Ultrasound-guided thermal ablation versus laparoscopic surgery for focal nodular hyperplasia of the liver: A retrospective controlled study

A novel m7G-related lncRNA risk model for predicting prognosis and evaluating the tumor immune microenvironment in colon carcinoma

Identification and validation of four photodynamic therapy related genes inhibiting MAPK and inducing cell cycle alteration in squamous cell carcinoma

Oncogenic circular RNA circ_0007534 contributes to paclitaxel resistance in endometrial cancer by sponging miR-625 and promoting ZEB2 expression

Brain morphological alterations and their correlation to tumor differentiation and duration in patients with lung cancer after platinum chemotherapy

BTK, the new kid on the (oncology) block?

CD44 expressed by myeloid cells promotes glioma invasion

Bevacizumab combined with re-irradiation in recurrent glioblastoma

Integrated multi-omics analysis identifies ENY2 as a predictor of recurrence and a regulator of telomere maintenance in hepatocellular carcinoma

Hepatobiliary Phase Features of Preoperative Gadobenate-Enhanced MR can Predict Early Recurrence of Hepatocellular Carcinoma in Patients Who Underwent Anatomical Hepatectomy

Case report: immunotherapy successfully treated brain metastasis in intrahepatic cholangiocarcinoma and literature review

Case report: Important considerations for a renal mass on a solitary kidney in an adult with history of childhood wilms tumor

High salt intake combined with hypertension elevated the risk of primary liver cancer: a prospective cohort study

Hyperprogressive disease in patients suffering from solid malignancies treated by immune checkpoint inhibitors: A systematic review and meta-analysis

Synergistic effects of nab-PTX and anti-PD-1 antibody combination against lung cancer by regulating the Pi3K/AKT pathway through the Serpinc1 gene

The role of adjuvant chemotherapy in the management of acute promyelocytic leukemia differentiation syndrome

Non-muscle invasive bladder cancer biomarkers beyond morphology

Robot-assisted vs. laparoscopic nephroureterectomy for upper urinary tract urothelial carcinoma: a systematic review and meta-analysis based on comparative studies

Segmentation of the cervical lesion region in colposcopic images based on deep learning

Elevated expression of LIF predicts a poor prognosis and promotes cell migration and invasion of clear cell renal cell carcinoma

Associations of clinical and circulating metabolic biomarkers with low physical fitness and function in adults with chronic lymphocytic leukemia

External validation study of endometrial cancer preoperative risk stratification model (ENDORISK)

Comprehensive analyses unveil novel genomic and immunological characteristics of micropapillary pattern in lung adenocarcinoma

pH-responsive graphene oxide loaded with targeted peptide and anticancer drug for OSCC therapy

Metastases to the thyroid gland: ultrasonographic findings and diagnostic value of fine-needle aspiration cytology

Discussion of tumor mutation burden as an indicator to predict efficacy of immune checkpoint inhibitors: A case report

Augmenting antibody response to EGF-depleting immunotherapy: Findings from a phase I trial of CIMAvax-EGF in combination with nivolumab in advanced stage NSCLC

Corrigendum: Downregulation of ATXN3 enhances the sensitivity to AKT inhibitors (Perifosine or MK-2206), but decreases the sensitivity to chemotherapeutic drugs (etoposide or cisplatin) in neuroblastoma cells

Mechanisms and prospects of circular RNAs and their interacting signaling pathways in colorectal cancer

The reporting of uveal melanoma cases to the cancer registry in North Carolina

Combined treatment with epigenetic agents enhances anti-tumor activity of MAGE-D4 peptide-specific T cells by upregulating the MAGE-D4 expression in glioma

LncRNA SCAMP1 disrupts the balance between miR-26a-5p and ZEB2 to promote osteosarcoma cell viability and invasion

Case Report: TEMPI syndrome: Report of three cases and treatment follow-up

Research trends and hotspots of breast cancer management during the COVID-19 pandemic: A bibliometric analysis

Growth-promoting function of the cGAS-STING pathway in triple-negative breast cancer cells

Investigation of the inhibition effect of 1,2,3,4,6-pentagalloyl-β-D-glucose on gastric cancer cells based on a network pharmacology approach and experimental validation

In vitro models for head and neck cancer: Current status and future perspective

Reduction of inter-observer variability using MRI and CT fusion in delineating of primary tumor for radiotherapy in lung cancer with atelectasis

Case Report: Upper limb dysfunction may be caused by chest wall mass excision: An enlightenment from a special case

Anti-Migratory Effect of Dipotassium Glycyrrhizinate on Glioblastoma Cell Lines: Microarray Data for the Identification of Key MicroRNA Signatures

High risk and early onset of cancer in Chinese patients with Peutz-Jeghers syndrome

DDX5 and DDX17—multifaceted proteins in the regulation of tumorigenesis and tumor progression

Efficacy and safety of radiotherapy/chemoradiotherapy combined with immune checkpoint inhibitors for locally advanced stages of esophageal cancer: A systematic review and meta-analysis

Sex-specific differences in immunogenomic features of response to immune checkpoint blockade

Preferred place of death and end-of-life care for adult cancer patients in Iran: A cross-sectional study

A combined predictive model based on radiomics features and clinical factors for disease progression in early-stage non-small cell lung cancer treated with stereotactic ablative radiotherapy

PD-L1 expression on circulating tumor cells can be a predictive biomarker to PD-1 inhibitors combined with radiotherapy and antiangiogenic therapy in advanced hepatocellular carcinoma

The clinical evaluation of atlas-based auto-segmentation for automatic contouring during cervical cancer radiotherapy

Insomnia in patients treated with checkpoint inhibitors for cancer: A meta-analysis

TElomeric repeat-containing RNA (TERRA): Physiological functions and relevance in cancer

Bioinformatics analysis and experimental verification of the prognostic and biological significance mediated by fatty acid metabolism related genes for hepatocellular carcinoma

Progressive multifocal leukoencephalopathy associated with chemotherapy induced lymphocytopenia in solid tumors – case report of an underestimated complication

Synthesis and anti-melanoma effect of 3-O-prenyl glycyrrhetinic acid against B16F10 cells via induction of endoplasmic reticulum stress-mediated autophagy through ERK/AKT signaling pathway

Efficacy and safety of camrelizumab plus transarterial chemoembolization in intermediate to advanced hepatocellular carcinoma patients: A prospective, multi-center, real-world study

Interpretable clinical visualization model for prediction of prognosis in osteosarcoma: a large cohort data study

Whole genome analysis reveals the genomic complexity in metastatic cutaneous squamous cell carcinoma

Survival and adverse events of elderly patients treated with sorafenib for hepatocellular carcinoma

Immunotherapy in non-small cell lung cancer: Past, present, and future directions

Sexual dysfunction as a challenge in treated breast cancer: in-depth analysis and risk assessment to improve individual outcomes

A novel defined m7G regulator signature to investigate the association between molecular characterization and clinical significance in lung adenocarcinoma

Positive Phospho-Focal Adhesion Kinase in Gastric Cancer Associates With Poor Prognosis After Curative Resection

Neoadjuvant Anlotinib and chemotherapy followed by minimally invasive esophagectomy in patients with locally advanced esophageal squamous cell carcinoma: Short-term results of an open-label, randomized, phase II trial

Interplay Between Chemotherapy-Activated Cancer Associated Fibroblasts and Cancer Initiating Cells Expressing CD44v6 Promotes Colon Cancer Resistance

Id2 exerts tumor suppressor properties in lung cancer through its effects on cancer cell invasion and migration

Construction of an immune-related gene signature for the prognosis and diagnosis of glioblastoma multiforme

Exploring the current molecular landscape and management of multiple myeloma patients with the t(11;14) translocation

Comprehensive analysis of the potential cuproptosis-related biomarker LIAS that regulates prognosis and immunotherapy of pan-cancers

Phase 1b clinical trial of pucotenlimab (HX008), a novel anti-PD-1 monoclonal antibody, combined with gemcitabine and cisplatin in the first-line treatment of metastatic triple-negative breast cancer

Hot flushes and sweating, sleep problems, joint and muscular discomfort, and physical and mental exhaustion in breast cancer survivors during the first 24 months of tamoxifen therapy: a prospective observational study

Retinoblastoma in Adults: Clinical Features, Gene Mutations and Treatment Outcomes: A Study of Six Cases

Case Report: A rare case of familial lung cancer requiring pneumonectomy in three male siblings

Clinicopathologic study of mantle cell lymphoma with epstein-barr virus infection: A case series and literature review

Corrigendum: Successful treatment of a patient with multiple-line relapsed extensive-stage small-cell lung cancer receiving penpulimab combined with anlotinib: A case report

Artificial intelligence in the radiomic analysis of glioblastomas: A review, taxonomy, and perspective

iRGD-modified exosomes-delivered BCL6 siRNA inhibit the progression of diffuse large B-cell lymphoma

Case report: Oligodendroglioma, IDH-mutant and 1p/19q-codeleted, associated with a germline mutation in PMS2

Complex metabolic interactions between ovary, plasma, urine, and hair in ovarian cancer

Research trends of artificial intelligence in pancreatic cancer: a bibliometric analysis

Long-Read Sequencing Annotation of the Transcriptome in DNA-PK Inactivated Cells

Range-shifter effects on the stray field in proton therapy measured with the variance–covariance method

Patient-Derived Organoid Facilitating Personalized Medicine in Gastrointestinal Stromal Tumor With Liver Metastasis: A Case Report

Transcriptional, chromatin, and metabolic landscapes of LDHA inhibitor–resistant pancreatic ductal adenocarcinoma

A systematic pan-cancer analysis of PXDN as a potential target for clinical diagnosis and treatment

Long-term follow-up of early stage HER2-positive breast cancer patients treated with trastuzumab: A population-based real world multicenter cohort study

Association of JAK/STAT genetic variants with cutaneous melanoma

Emerging role of non-coding RNAs in glucose metabolic reprogramming and chemoresistance in colorectal cancer

Using deep learning to distinguish malignant from benign parotid tumors on plain computed tomography images

Receptor tyrosine kinase (RTK) targeting in pediatric high-grade glioma and diffuse midline glioma: Pre-clinical models and precision medicine

LCS-1 inhibition of superoxide dismutase 1 induces ROS-dependent death of glioma cells and degradates PARP and BRCA1

NAT10 acetylates BCL-XL mRNA to promote the proliferation of multiple myeloma cells through PI3K-AKT pathway

Five-lipoxygenase-activating protein-mediated CYLD attenuation is a candidate driver in hepatic malignant lesion

Identification of a novel FGFR2-KIAA1217 fusion in esophageal gastrointestinal stromal tumours: A case report

FBP1/miR-24-1/enhancer axis activation blocks renal cell carcinoma progression via Warburg effect

Efficacy of transarterial chemoembolization monotherapy or combination conversion therapy in unresectable hepatocellular carcinoma: A systematic review and meta-analysis

ELAVL1 promotes prostate cancer progression by interacting with other m6A regulators

Light flash and odor during proton beam therapy for pediatric patients: a prospective observational study

EGFR amplification is a putative resistance mechanism for NSCLC–LM patients with TKI therapy and is associated with poor outcome

MiR-27a-3p binds to TET1 mediated DNA demethylation of ADCY6 regulates breast cancer progression via epithelial-mesenchymal transition

What Plasma Can Tell Us When Tissue Cannot: A Case Report of Genomic Testing in mCRPC and Clinical Response to Treatment With the PARP Inhibitor Rucaparib

Differentiation between glioma recurrence and treatment effects using amide proton transfer imaging: A mini-Bayesian bivariate meta-analysis

A comprehensive comparison of circulating tumor cells and breast imaging modalities as screening tools for breast cancer in Chinese women

Cyclic adenosine monophosphate/phosphodiesterase 4 pathway associated with immune infiltration and PD-L1 expression in lung adenocarcinoma cells

Opportunities and challenges of targeting c-Met in the treatment of digestive tumors

Predictive value of Leukocyte ImmunoTest (LIT™) in cancer patients: a prospective cohort study

Exosome-transmitted miR-3124-5p promotes cholangiocarcinoma development via targeting GDF11

Emerging role of lncRNAs in drug resistance mechanisms in head and neck squamous cell carcinoma

Multi-omics analysis of expression and prognostic value of NSUN members in prostate cancer

Identification of a novel RMST-ALK rearrangement in advanced lung adenocarcinoma and durable response to ceritinib: A case report

SAMHD1 as a prognostic and predictive biomarker in stage II colorectal cancer: A multicenter cohort study

CXCL5: A coachman to drive cancer progression

Mortality due to respiratory system disease and lung cancer among female workers exposed to chrysotile in Eastern China: A cross-sectional study

State-of-the-art combination treatment strategies for advanced stage non–small cell lung cancer

Lipid metabolism in ferroptosis and ferroptosis-based cancer therapy

C-reactive protein provides superior prognostic accuracy than the IMDC risk model in renal cell carcinoma treated with Atezolizumab/Bevacizumab

Digital quantitative tissue image analysis of hypoxia in resected pancreatic ductal adenocarcinomas

Case report: 125I seed implantation for rare malignant solitary fibrous tumor in the pelvic cavity: a case report

Risk of progression in patients with chronic atrophic gastritis: A retrospective study

Differences in the clinical characteristics of papillary thyroid microcarcinoma located in the isthmus ≤5 mm and >5mm in diameter

The CURB65 score predicted 180-day mortality of non-small cell lung carcinoma patients with immune checkpoint inhibitor-associated pneumonitis: A pilot retrospective analysis

Efficacy and safety of apatinib monotherapy for patients with advanced breast cancer: a systematic review and meta-analysis

Apparent diffusion coefficient histogram analysis for differentiating solid ovarian tumors

An updated network meta-analysis of EGFR-TKIs and combination therapy in the first-line treatment of advanced EGFR mutation positive non-small cell lung cancer

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Contribution of MMP14-expressing cancer-associated fibroblasts in the tumor immune microenvironment to progression of colorectal cancer

Content Provider	frontiers
Author	Makutani, Yusuke Kawakami, Hisato Tsujikawa, Takahiro Yoshimura, Kanako Chiba, Yasutaka Ito, Akihiko Kawamura, Junichiro Haratani, Koji Nakagawa, Kazuhiko
Abstract	Matrix metalloproteinase 14 (MMP14) expression is implicated in progression of colorectal cancer, but its role in the tumor microenvironment (TME) has been unclear. The relevance of MMP14 to colorectal cancer progression was explored by analysis of transcriptomic data for colorectal adenocarcinoma patients (n = 592) in The Cancer Genome Atlas. The role of MMP14 in the TME was investigated in a retrospective analysis of tumor samples from 86 individuals with stage III colorectal cancer by single cell–based spatial profiling of MMP14 expression as performed by 12-color multiplex immunohistochemistry (mIHC). Analysis of gene expression data revealed that high MMP14 expression was associated with tumor progression and implicated both cancer-associated fibroblasts (CAFs) and tumor-associated macrophages in such progression. Spatial profiling by mIHC revealed that a higher percentage of MMP14+ cells among intratumoral CAFs (MMP14+ CAF/CAF ratio) was associated with poorer relapse-free survival. Multivariable analysis including key clinical factors identified the MMP14+ CAF/CAF ratio as an independent poor prognostic factor. Moreover, the patient subset with both a high MMP14+ CAF/CAF ratio and a low tumor-infiltrating lymphocyte density showed the worst prognosis. Our results suggest that MMP14+ CAFs play an important role in progression of stage III colorectal cancer and may therefore be a promising therapeutic target.
ISSN	2234943X
DOI	10.3389/fonc.2022.956270
Volume Number	12
Journal	Frontiers in Oncology
Language	English
Publisher Date	2022-08-16
Access Restriction	Open
Subject Keyword	Multiplex immunohistochemistry (mIHC) Matrix metalloproteinase 14 (MMP14) Colorectal cancer M2 tumor-associated macrophages (M2-TAMs) Cancer-associated fibroblast (CAF)
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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