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Glycogen Synthase Regulation
| Content Provider | AK Lectures |
|---|---|
| Description | Glycogen synthase is a key regulatory protein of glycogen synthesis and degradation. Not only do the cells use glycogen synthase for glycogenesis but they also use it to regulate the rate at which it takes place. Glycogen synthase can exist in two forms. Glycogen synthase a exists in the active form while glycogen synthase b exists predominantly in the inactive form. When there is no need to build glycogen within our cells, protein kinase A and glycogen synthase kinase (among other kinases) will phosphorylate glycogen synthase a at specific points. This will transform it into glycogen synthase b and inactivate the synthesis of glycogen. Although glycogen synthase b is almost always in the inactive form, large concentrations of glucose 6-phosphate will act as allosteric activators and convert the inactive glycogen synthase b into the active form. |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Biochemistry glycogenesis protein degradation forms glycogen synthase b |
| Content Type | Video |
| Educational Role | Teacher Student |
| Educational Use | Self Learning Lecture Reading |
| Resource Type | Video Lecture |
| Education Level | Under Graduate |
| Subject | Biochemistry Human physiology |
