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UDP-Glucose and Glycogen Elongation
| Content Provider | AK Lectures |
|---|---|
| Description | In order to attach a glucose molecule onto a growing polysaccharide chain, that glucose molecule must be activated. Once activated, the molecule will be reactive enough to attach onto the growing glycogen chain. Our cells use an enzyme called UDP-glucose pyrophosphorylase to transform a glucose 1-phosphate into a uridine diphosphate glucose. This reaction produces a pyrophosphate, which then is hydrolyzed by water to form two orthophosphate molecules. This second step drives the reaction forward. Once the activated UDP-glucose is formed, an enzyme called glycogen synthase catalyzes its attachment onto the growing glycogen chain. Glycogen synthase catalyzes the formation of alpha-1,4-glycosidic bonds and requires a primer to actually begin. |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Biochemistry Glycogen synthase catalyzes reactive form attachment UDP-glucose pyrophosphate molecule formation water |
| Content Type | Video |
| Educational Role | Teacher Student |
| Educational Use | Self Learning Lecture Reading |
| Resource Type | Video Lecture |
| Education Level | Under Graduate |
| Subject | Biochemistry Human physiology |
