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Glucagon Signal Pathway
| Content Provider | AK Lectures |
|---|---|
| Description | What initiates the break down of glycogen in liver cells? During times of starvation, when the blood glucose levels are low, the alpha cells of the pancreas release a peptide hormone called glucagon. Glucagon binds to seven transmembrane receptors found on liver cells, which in turns initiates a signal transduction pathway that ultimately leads to the break down of glycogen into glucose. In addition, epinephrine, a tyrosine-based hormone released by the adrenal medulla, binds to the alpha-adrenergic receptor and initiates the phosphoinositide cascade. This releases calcium ions into the cytoplasm from the endoplasmic reticulum, which helps initiate glycogen breakdown. |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Biochemistry cytoplasm starvation medulla glucose cells glucagon epinephrine glycogen signal transduction pathway addition |
| Content Type | Video |
| Educational Role | Teacher Student |
| Educational Use | Self Learning Lecture Reading |
| Resource Type | Video Lecture |
| Education Level | Under Graduate |
| Subject | Biochemistry Human physiology |