NDLI: Proof of Concept: Miracle Drug Encapsulation

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Proof of Concept: Miracle Drug Encapsulation

Content Provider	TeachEngineering: STEM curriculum for K-12
Author	Ketchum, Megan Lee, Andrea
Copyright Year	2016
Description	Students experience the engineering design process as they design, fabricate, test and redesign their own methods for encapsulation of a (hypothetical) new miracle drug. The objective is to delay the drug release by a certain time and have a long release duration—patterned after the timed release requirements of many real-world pharmaceuticals that are released from a polymer shell via diffusion in the body. Students experience the engineering design process as they design, fabricate, test and redesign their own methods for encapsulation of a (hypothetical) new miracle drug. As if they are engineers, teams make large-size prototypes to test proof of concept. They use household materials (tape, paper towels, plastic wrap, weed-barrier fabric, glues, etc.) to attach a coating to a porous "shell" (a perforated plastic Wiffle® ball) containing the medicine (colored drink mix powder). The objective is to delay the drug release by a certain time and have a long release duration—patterned after the timed release requirements of many real-world pharmaceuticals that are released from a polymer shell via diffusion in the body. Guided by a worksheet, teams go through at least three design/test iterations, aiming to achieve a solution close to the target time release constraints.
Language	English
Access Restriction	Open
Rights Holder	Regents of The University of Colorado University of Houston
Subject Keyword	Biology Chemistry Life Science Science and Technology Polymer Encapsulation Diffusion Medical Pharmaceutical Drug Design Biomedical Engineering Chemical Engineer Drug Delivery Biomedical Prototype Duration Solubility Chemical Engineering
Content Type	Text Video
Time Required	PT4H15M
Education Level	Class IX Class X Class XI Class XII
Pedagogy	Experimental Activity Lecture cum Demonstration
Resource Type	Hands-on
Subject	Chemistry Biology Technical

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